{"id":"W2553768844","doi":"10.1182/blood.v118.21.3316.3316","title":"Safety of Recombinant Activated Factor VII (rFVIIa) in Patients with Congenital Hemophilia with Inhibitors: Overall Dose Exposure and Intervals Following >240 Mcg/Kg Doses Across Trial, Registry and Diary Studies,","year":2011,"lang":"en","type":"article","venue":"Blood","topic":"Hemophilia Treatment and Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Medicine; Adverse effect; Data monitoring committee; Bleed; Hemostasis; Clinical trial; Randomized controlled trial; Observational study; Prospective cohort study; Pediatrics; Emergency medicine; Surgery; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01062218,0.0005377157,0.001475233,0.0007741654,0.0002554737,0.001301436,0.0005041463,0.0007648363,0.002051619],"category_scores_gemma":[0.01402993,0.0003808598,0.003495331,0.001789795,0.0005282845,0.001028744,0.0006276467,0.001065251,0.0002830982],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005858648,"about_ca_system_score_gemma":0.0007710081,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005008665,"about_ca_topic_score_gemma":0.0006844296,"domain_scores_codex":[0.9898431,0.006287913,0.001691413,0.001141591,0.0007721063,0.0002640545],"domain_scores_gemma":[0.9773932,0.009090305,0.009207415,0.002504003,0.001177828,0.0006272726],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.5635909,0.002136055,0.3493736,0.004549218,0.03340526,0.0001749045,0.000381487,0.0009499188,0.002606899,0.0002197672,0.001456919,0.04115495],"study_design_scores_gemma":[0.1158908,0.1015654,0.7340291,0.0007012307,0.0363062,0.0008105033,0.0003794387,0.001699446,0.003028886,0.0003213478,0.005139653,0.0001279909],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9796244,0.0152473,0.0006402297,0.0001063151,0.00004794209,0.0005840922,0.002477248,0.00002309406,0.001249294],"genre_scores_gemma":[0.9956749,0.001470446,0.0003680175,0.00008274784,0.00004278326,0.0002982059,0.001843856,0.00000952602,0.0002096065],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01062218,"threshold_uncertainty_score":0.05617607,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03658406872647954,"score_gpt":0.2923937353953448,"score_spread":0.2558096666688653,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}