{"id":"W2553852565","doi":"10.1111/tpj.13427","title":"Biosynthesis of the psychotropic plant diterpene salvinorin A: Discovery and characterization of the <i>Salvia divinorum</i> clerodienyl diphosphate synthase","year":2016,"lang":"en","type":"article","venue":"The Plant Journal","topic":"Plant biochemistry and biosynthesis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":76,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia; University of Calgary","funders":"National Institute of Mental Health; Natural Sciences and Engineering Research Council of Canada; University of California, Davis; Canada Research Chairs; National Science Foundation; National Institutes of Health; Rural Development Administration","keywords":"Diterpene; Salvia; ATP synthase; Traditional medicine; Chemistry; Pharmacology; Stereochemistry; Medicine; Biochemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001070281,0.0003194883,0.0002350085,0.0001794455,0.000108494,0.0003303502,0.0001087213,0.0002018028,0.0003193107],"category_scores_gemma":[0.0001183325,0.00007786064,0.0003147253,0.0001930634,0.0001303494,0.000220647,0.0001664298,0.0002836396,0.0003129838],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002613316,"about_ca_system_score_gemma":0.0002897495,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006183229,"about_ca_topic_score_gemma":0.0008294031,"domain_scores_codex":[0.9999521,0.000005744976,0.000004660301,0.00001562835,0.00001310891,0.000008795008],"domain_scores_gemma":[0.9999259,0.000009803754,0.00001664459,0.000009775354,0.00001580921,0.00002199721],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003170612,0.000009615831,0.0004766955,0.00004561625,0.000005330846,0.0000640427,0.00002165162,0.0001249797,0.9959642,0.00009417717,0.00002743355,0.003134662],"study_design_scores_gemma":[0.0000108738,0.0001674832,0.01188587,0.00001100123,0.00003845998,0.0006895187,0.00008837967,0.001898298,0.974133,0.00020216,0.01086356,0.00001132445],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.983777,0.005316128,0.007201461,0.0003423241,0.00002413927,0.00005596194,0.001285062,0.00008323693,0.001914588],"genre_scores_gemma":[0.9817176,0.003501179,0.007860228,0.000094651,0.00001789672,0.00002170836,0.003843015,0.00002529814,0.002918529],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006183229,"threshold_uncertainty_score":0.001896143,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007640761184808861,"score_gpt":0.1803633431635267,"score_spread":0.1727225819787179,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}