{"id":"W2554198250","doi":"10.1097/tp.0000000000001578","title":"Necroptosis Is Involved in CD4+ T Cell-Mediated Microvascular Endothelial Cell Death and Chronic Cardiac Allograft Rejection","year":2016,"lang":"en","type":"article","venue":"Transplantation","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University; London Health Sciences Centre","funders":"Canadian Institutes of Health Research","keywords":"Necroptosis; Medicine; Endothelial stem cell; Programmed cell death; Immunology; Heart transplantation; Transplantation; Cancer research; Biology; Apoptosis; Internal medicine; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002146187,0.0002627396,0.0001353805,0.0001529602,0.000124857,0.0001959337,0.0001270406,0.000285099,0.001871123],"category_scores_gemma":[0.0001033061,0.00006452424,0.0001729511,0.0000812429,0.0001910085,0.0001839201,0.0001850372,0.0004756595,0.0003034324],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002285904,"about_ca_system_score_gemma":0.0001537156,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001088147,"about_ca_topic_score_gemma":0.0001305353,"domain_scores_codex":[0.9998673,0.00002726029,0.00001589902,0.00002789185,0.00002241134,0.00003925953],"domain_scores_gemma":[0.9998503,0.00001033445,0.00007290322,0.000008388609,0.00001318199,0.00004475625],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007627994,0.00009665087,0.004230911,0.0001546055,0.00001943519,0.0005874434,0.00003685187,0.0001120505,0.989514,0.0001928213,0.000113034,0.004179304],"study_design_scores_gemma":[0.0002893724,0.002518391,0.1391025,0.0001200124,0.0001996503,0.01281159,0.0002204265,0.00289052,0.8310544,0.001180559,0.009596502,0.00001601581],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9909115,0.005066738,0.002241567,0.0001280671,0.000026212,0.00003637448,0.000142596,0.00006459444,0.001382274],"genre_scores_gemma":[0.9962658,0.001153478,0.0009705859,0.00005403951,0.00001840791,0.00002880986,0.0002034113,0.000006083249,0.001299407],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001871123,"threshold_uncertainty_score":0.006259501,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005576465336080394,"score_gpt":0.1998134207496083,"score_spread":0.194236955413528,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}