{"id":"W2554404398","doi":"10.1038/srep36685","title":"Molecular basis for epitope recognition by non-neutralizing anti-gp41 antibody F240","year":2016,"lang":"en","type":"article","venue":"Scientific Reports","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; McGill University; Centre Hospitalier de l’Université de Montréal","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research; National Institutes of Health; Styrelsen för Internationellt Utvecklingssamarbete; Fonds de Recherche du Québec - Santé; National Institute of Allergy and Infectious Diseases; Bill and Melinda Gates Foundation","keywords":"Gp41; Epitope; Antibody-dependent cell-mediated cytotoxicity; Glycoprotein; Context (archaeology); Virology; Monoclonal antibody; Trimer; Antibody; Biology; Chemistry; Cell biology; Molecular biology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007421284,0.0002104915,0.0001117455,0.0001065583,0.0001112101,0.0002107643,0.000276115,0.0003507095,0.00118862],"category_scores_gemma":[0.0001260907,0.00007909859,0.0001820891,0.00004581613,0.0002026031,0.0001852918,0.0001355403,0.0002984372,0.0002601348],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001903358,"about_ca_system_score_gemma":0.0001216756,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002364377,"about_ca_topic_score_gemma":0.0001015267,"domain_scores_codex":[0.9999462,0.000008520844,0.000002932691,0.000009743442,0.00001766165,0.00001491347],"domain_scores_gemma":[0.9999504,0.0000124525,0.00001380572,0.000005403257,0.000007479327,0.00001039317],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001604751,0.00003995193,0.0009345544,0.00002103641,0.000005090767,0.0002447161,0.00001549918,0.0001988742,0.9964823,0.0004732166,0.00002467238,0.001399653],"study_design_scores_gemma":[0.00006500771,0.0006152028,0.01031048,0.000008071077,0.00001586661,0.002826392,0.00004908289,0.004096672,0.9797075,0.0007998231,0.001499758,0.000006052116],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971569,0.0003720836,0.001329766,0.00005124881,0.000004296374,0.000009103659,0.00003584636,0.00001461877,0.001026198],"genre_scores_gemma":[0.9989729,0.0001509086,0.0005436342,0.00002445698,0.000003631973,0.000003466006,0.00007511659,0.000002650511,0.0002233353],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00118862,"threshold_uncertainty_score":0.003976285,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0180552355216139,"score_gpt":0.2890117277552829,"score_spread":0.270956492233669,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}