{"id":"W2554617148","doi":"10.1128/mcb.00421-16","title":"Suppressor of Fused Chaperones Gli Proteins To Generate Transcriptional Responses to Sonic Hedgehog Signaling","year":2016,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"Hedgehog Signaling Pathway Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":68,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Key Research and Development Program of China; Canadian Cancer Society Research Institute; National Natural Science Foundation of China","keywords":"Biology; Hedgehog signaling pathway; Suppressor; Signal transduction; Hedgehog; Cell biology; Sonic hedgehog; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003209571,0.0002636105,0.0003217653,0.0001302062,0.00009850351,0.00001182438,0.000230888,0.0002001774,0.00002898648],"category_scores_gemma":[0.0001888001,0.00020096,0.0001272176,0.000121854,0.0001792046,0.000003308253,0.0001679039,0.0000552946,0.000014336],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001231766,"about_ca_system_score_gemma":0.00007506384,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001413936,"about_ca_topic_score_gemma":0.000008299679,"domain_scores_codex":[0.9982457,0.0002424995,0.0003341934,0.0006314506,0.0001182454,0.0004279576],"domain_scores_gemma":[0.9992176,0.00002922848,0.00006601412,0.0003512942,0.0001482999,0.0001876131],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003966351,0.00004948922,0.0005341581,0.00002451079,0.0001093984,0.00001161965,0.0001373218,0.00002465182,0.9964587,0.0007696676,0.00004021098,0.001443644],"study_design_scores_gemma":[0.0006521583,0.00107769,0.0003649977,0.00003817311,0.0000271226,0.000007154439,0.00003568969,0.000005108716,0.9878357,0.0001633524,0.009500877,0.000291953],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8504579,0.002297804,0.1456914,0.0008726016,0.000106614,0.0004056483,0.000114266,0.00001645096,0.00003726228],"genre_scores_gemma":[0.9955016,0.00004375136,0.003326453,0.000510694,0.0001286726,0.0001178073,0.00003511585,0.00003704514,0.0002988384],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1450437,"threshold_uncertainty_score":0.8194911,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01696446705278873,"score_gpt":0.2473070595256441,"score_spread":0.2303425924728554,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}