{"id":"W2554617148","doi":"10.1128/mcb.00421-16","title":"Suppressor of Fused Chaperones Gli Proteins To Generate Transcriptional Responses to Sonic Hedgehog Signaling","year":2016,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"Hedgehog Signaling Pathway Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":68,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Key Research and Development Program of China; Canadian Cancer Society Research Institute; National Natural Science Foundation of China","keywords":"Biology; Hedgehog signaling pathway; Suppressor; Signal transduction; Hedgehog; Cell biology; Sonic hedgehog; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001065055,0.0002738485,0.0001513759,0.0001865313,0.0001049079,0.0001439717,0.0001682992,0.0001435692,0.000768238],"category_scores_gemma":[0.0001007238,0.000101535,0.0001681149,0.00008450927,0.0001960114,0.00009871207,0.0002139685,0.0002953483,0.0002318904],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002247596,"about_ca_system_score_gemma":0.0001523702,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003454764,"about_ca_topic_score_gemma":0.0006556885,"domain_scores_codex":[0.9999427,0.000009897448,0.00000478834,0.00000979703,0.00001970721,0.00001320075],"domain_scores_gemma":[0.999911,0.00001264415,0.00002252709,0.00001213122,0.000008629397,0.00003315221],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003376737,0.000007175077,0.00006872251,0.000007930809,0.000002458038,0.00003066943,0.00000534676,0.00002975882,0.9993511,0.00009881358,0.00001684007,0.0003474831],"study_design_scores_gemma":[0.00001538811,0.0001445838,0.003727801,0.000003641984,0.00001121252,0.0005288686,0.00001953817,0.001250227,0.9905963,0.0001084986,0.003589479,0.000004556316],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957762,0.0004365817,0.002842714,0.00005390761,0.00002037424,0.00001081594,0.000135645,0.00007718434,0.000646632],"genre_scores_gemma":[0.9962201,0.0001602722,0.001284815,0.00002213346,0.000005460998,0.000008393689,0.0003415169,0.00002512816,0.001932322],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000768238,"threshold_uncertainty_score":0.002570033,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01696446705278873,"score_gpt":0.2473070595256441,"score_spread":0.2303425924728554,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}