{"id":"W2554762370","doi":"10.1038/srep36694","title":"Aflibercept and Ang1 supplementation improve neoadjuvant or adjuvant chemotherapy in a preclinical model of resectable breast cancer","year":2016,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Angiogenesis and VEGF in Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Sunnybrook Health Science Centre","funders":"Canadian Institutes of Health Research; Cure Brain Cancer Foundation; University of Toronto","keywords":"Medicine; Bevacizumab; Aflibercept; Adjuvant; Breast cancer; Oncology; Neoadjuvant therapy; Chemotherapy; Internal medicine; Angiopoietin receptor; Triple-negative breast cancer; Cancer; Angiogenesis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001924892,0.0005811047,0.0005516462,0.0003257493,0.0001402677,0.0002869112,0.0002830148,0.0003441433,0.001402826],"category_scores_gemma":[0.0001226339,0.0001593854,0.0002178371,0.0001627316,0.0002088773,0.0003808133,0.00009389835,0.001111824,0.0003176141],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003269191,"about_ca_system_score_gemma":0.0003810385,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000945211,"about_ca_topic_score_gemma":0.002669039,"domain_scores_codex":[0.999889,0.00001963943,0.000009895199,0.00002171544,0.00002301677,0.00003673267],"domain_scores_gemma":[0.9998802,0.00001342072,0.00003489876,0.00001058486,0.000009893178,0.00005092278],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.005699966,0.003444297,0.0002549858,0.0001202198,0.00002460046,0.00005637071,0.00002968738,0.0004314387,0.9753651,0.00009497433,0.0004189888,0.01405938],"study_design_scores_gemma":[0.001180488,0.03574812,0.003963947,0.00001622933,0.00009442579,0.0003158186,0.00003534732,0.00177822,0.9519327,0.00009371938,0.004822789,0.00001812171],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951747,0.001753819,0.0007912269,0.0002543037,0.0001144896,0.00009016867,0.0004597293,0.0001157379,0.001245756],"genre_scores_gemma":[0.990176,0.001951949,0.002297036,0.0001416753,0.00004418393,0.0001655392,0.0008959713,0.00003118366,0.004296434],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001402826,"threshold_uncertainty_score":0.004692912,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02529667789105944,"score_gpt":0.3276227198816092,"score_spread":0.3023260419905498,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}