{"id":"W2554766738","doi":"10.1182/blood.v112.11.2576.2576","title":"Human Mesenchymal Stromal Cells (MSCs) Suppress Cytotoxicity of Natural Killer (NK) Cell Lines and Can Be Targets for NK-Mediated Cytolysis","year":2008,"lang":"en","type":"article","venue":"Blood","topic":"Mesenchymal stem cell research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Mesenchymal stem cell; K562 cells; Cytolysis; Interleukin 12; Natural killer cell; Perforin; Cytotoxicity; Biology; Flow cytometry; Lymphokine-activated killer cell; Granzyme; Cell culture; Immunophenotyping; Cell; NK-92; Immunology; Interleukin 21; Cell biology; Immune system; Cytotoxic T cell; In vitro; T cell; Leukemia; CD8","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001243045,0.0002942976,0.0002917147,0.0001471216,0.00006554084,0.0002605002,0.00009597905,0.0001761447,0.001502877],"category_scores_gemma":[0.0001253768,0.00008124615,0.0002134528,0.0001394171,0.0001505958,0.0001299438,0.0002012155,0.0004709494,0.0004135944],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007742248,"about_ca_system_score_gemma":0.0001161385,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002038808,"about_ca_topic_score_gemma":0.0002950519,"domain_scores_codex":[0.9997402,0.00004411201,0.00004314891,0.00003262062,0.0000942077,0.0000457305],"domain_scores_gemma":[0.9998436,0.00004427166,0.00004271628,0.00001992107,0.00001858567,0.00003087132],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002470425,0.00004615305,0.0002910388,0.00005827669,0.000007202957,0.00004590245,0.00001820987,0.00005783244,0.9972133,0.00005157247,0.00004109403,0.00192239],"study_design_scores_gemma":[0.0000240172,0.0004592882,0.003350537,0.000006199986,0.00002086659,0.0001917639,0.00003302551,0.0003794847,0.9936587,0.00002613981,0.001847829,0.000002110866],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9935048,0.002243528,0.002518383,0.00006517221,0.00005703715,0.00003218394,0.0003345208,0.00006472272,0.001179651],"genre_scores_gemma":[0.9969112,0.0006622578,0.0008992034,0.00003730496,0.00001877031,0.00003279253,0.0003695664,0.00001208811,0.001056871],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001502877,"threshold_uncertainty_score":0.005027592,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02656530308492202,"score_gpt":0.2817183281940935,"score_spread":0.2551530251091715,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}