{"id":"W2554841376","doi":"10.1016/j.cryobiol.2016.09.006","title":"Clinical trials of cell based and cell based gene enhanced therapies: The Ottawa experience","year":2016,"lang":"en","type":"article","venue":"Cryobiology","topic":"Biomedical Ethics and Regulation","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ottawa Hospital","funders":"","keywords":"Cell; Clinical trial; Medicine; Gene; Computational biology; Bioinformatics; Biology; Internal medicine; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003108495,0.0000973127,0.0004659038,0.00003862486,0.000044873,0.000002738295,0.00009682922,0.0003575713,0.0004463056],"category_scores_gemma":[0.0006793023,0.00003947893,0.0001322898,0.00007094305,0.001886333,0.00001197619,0.00002116603,0.0001380407,0.000006591313],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008577106,"about_ca_system_score_gemma":0.0001630172,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007642699,"about_ca_topic_score_gemma":0.000002722102,"domain_scores_codex":[0.9980853,0.0007358724,0.0006832458,0.00024034,0.0001010119,0.0001541892],"domain_scores_gemma":[0.996182,0.003049104,0.0002903546,0.0002920127,0.00009459731,0.0000919717],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002409226,0.0001175815,0.001276505,0.00003521649,0.00001326279,0.000001116743,0.0001923771,3.727488e-7,0.9807538,0.00009793622,0.0002285053,0.0170424],"study_design_scores_gemma":[0.006858471,0.001161139,0.02047681,0.00008735668,0.00007273976,0.000002268569,0.0001467884,0.000385112,0.9410355,0.000597642,0.02905187,0.0001242759],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9380224,0.00106971,0.04432056,0.0151373,0.0004781332,0.0004316269,0.00002045344,0.00002163781,0.0004981242],"genre_scores_gemma":[0.9959135,0.0002216724,0.001367383,0.002023825,0.0001829746,0.00001926802,0.000009924383,0.00000797884,0.0002534682],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05789104,"threshold_uncertainty_score":0.6950274,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08326709378740148,"score_gpt":0.4009467968575973,"score_spread":0.3176797030701958,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}