{"id":"W2555162116","doi":"10.1182/blood.v106.11.4371.4371","title":"Short Nucleotide Insertions in the MCL-1 Promoter Affect Its Gene Expression.","year":2005,"lang":"en","type":"article","venue":"Blood","topic":"Chronic Lymphocytic Leukemia Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Royal University Hospital","funders":"","keywords":"Luciferase; Transfection; Molecular biology; HeLa; Biology; Reporter gene; Plasmid; Phorbol; K562 cells; Cell culture; Gene; Gene expression; Signal transduction; Biochemistry; Protein kinase C; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001978615,0.0003037537,0.0001652111,0.000147841,0.00009872102,0.0002232982,0.0001851126,0.0002048627,0.001559334],"category_scores_gemma":[0.0003179698,0.000136868,0.0002859963,0.000110976,0.0001998068,0.0001401112,0.000265178,0.0006071569,0.000553398],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001796126,"about_ca_system_score_gemma":0.0001587439,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002241901,"about_ca_topic_score_gemma":0.0003712295,"domain_scores_codex":[0.9998203,0.00003876651,0.00002142957,0.00003791677,0.000048514,0.00003310889],"domain_scores_gemma":[0.9996818,0.0001062596,0.0001121731,0.00002632415,0.00002438608,0.00004907743],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001647989,0.00002887263,0.0007273043,0.00004638822,0.000005318307,0.00008242039,0.00001448372,0.00005076044,0.9971195,0.00005658801,0.00003406218,0.001669552],"study_design_scores_gemma":[0.00003923264,0.0007044587,0.008272988,0.00002813596,0.00004543502,0.001326041,0.00004262644,0.001371847,0.9819687,0.00008545887,0.006103642,0.00001140168],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9906213,0.001885239,0.006084429,0.0001265736,0.00006516819,0.00003431611,0.0005558402,0.0001095201,0.0005175393],"genre_scores_gemma":[0.9916567,0.0006913545,0.005099518,0.00007185464,0.00001965617,0.00002636926,0.001324182,0.00003110029,0.001079444],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001559334,"threshold_uncertainty_score":0.005216539,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03127767896194254,"score_gpt":0.3132241160925438,"score_spread":0.2819464371306012,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}