{"id":"W2555227854","doi":"10.3390/vaccines4040044","title":"Homologous Prime-Boost Vaccination with OVA Entrapped in Self-Adjuvanting Archaeosomes Induces High Numbers of OVA-Specific CD8+ T Cells that Protect Against Subcutaneous B16-OVA Melanoma","year":2016,"lang":"en","type":"article","venue":"Vaccines","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Research Council Canada","funders":"Government of Ontario; Ontario Institute for Cancer Research","keywords":"Vaccination; CD8; Homologous chromosome; Biology; Immunology; Immune system; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004376737,0.0004666547,0.0007289908,0.0005255174,0.0002020574,0.00002489007,0.0004835685,0.000406023,0.000426351],"category_scores_gemma":[0.00005725177,0.0003098227,0.0001342141,0.0004325213,0.0001177025,0.0002773623,0.0001076151,0.0003419971,0.0001105644],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001008106,"about_ca_system_score_gemma":0.0001410355,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002641475,"about_ca_topic_score_gemma":0.00005995206,"domain_scores_codex":[0.9973677,0.0005654456,0.0006637577,0.0005749331,0.0001045016,0.000723647],"domain_scores_gemma":[0.9981558,0.0005792555,0.000526474,0.0005657753,0.0001470928,0.00002554806],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004175468,0.0003160529,0.006860757,0.00005910846,0.0003525382,0.00007910437,0.002121991,0.000005040398,0.9418152,0.0001103775,0.0001228801,0.0439815],"study_design_scores_gemma":[0.004736349,0.000909937,0.05695747,0.0002921812,0.00003428264,0.0003722142,0.0004249774,9.132161e-7,0.9332252,0.00007682195,0.002508457,0.0004612363],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9919842,0.005561286,0.0001023515,0.0003913613,0.0005620952,0.001007391,0.00003207953,0.0001819883,0.0001772376],"genre_scores_gemma":[0.9957271,0.002620749,0.0003099891,0.00005119305,0.00004208164,0.00007312537,0.00003819555,0.00006466505,0.001072965],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05009671,"threshold_uncertainty_score":0.9999354,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008788475070272037,"score_gpt":0.204327717848626,"score_spread":0.195539242778354,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}