{"id":"W2555227854","doi":"10.3390/vaccines4040044","title":"Homologous Prime-Boost Vaccination with OVA Entrapped in Self-Adjuvanting Archaeosomes Induces High Numbers of OVA-Specific CD8+ T Cells that Protect Against Subcutaneous B16-OVA Melanoma","year":2016,"lang":"en","type":"article","venue":"Vaccines","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Research Council Canada","funders":"Government of Ontario; Ontario Institute for Cancer Research","keywords":"Vaccination; CD8; Homologous chromosome; Biology; Immunology; Immune system; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001161186,0.0004127639,0.0002048137,0.0001822764,0.00007597993,0.0001714113,0.0001073665,0.0002835717,0.0009587329],"category_scores_gemma":[0.00009400443,0.000162176,0.0001795549,0.00006396136,0.00016064,0.000187059,0.0001436427,0.0007781175,0.0003356693],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001287305,"about_ca_system_score_gemma":0.000144892,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001742023,"about_ca_topic_score_gemma":0.0003377084,"domain_scores_codex":[0.999913,0.00001092767,0.000008032835,0.00002191474,0.00001545457,0.00003070975],"domain_scores_gemma":[0.9999108,0.00001455838,0.00002468185,0.0000133434,0.000006785089,0.00002974053],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002298724,0.0000827674,0.0001858096,0.00002758162,0.0000032458,0.00001569004,0.00001185303,0.00004809251,0.9981732,0.00002607864,0.00001943551,0.001176437],"study_design_scores_gemma":[0.00004150294,0.002528722,0.004900036,0.00001157891,0.00002032652,0.0001227813,0.00002673403,0.0006080745,0.9908358,0.00003848673,0.0008619073,0.000004128879],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977055,0.000349587,0.001008903,0.00003003745,0.00002181741,0.00003455005,0.0001266987,0.00006175663,0.0006611911],"genre_scores_gemma":[0.9964558,0.0003152946,0.001241015,0.00003508265,0.00001089885,0.00004050577,0.0002163348,0.00001618132,0.001668723],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009587329,"threshold_uncertainty_score":0.003207326,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008788475070272037,"score_gpt":0.204327717848626,"score_spread":0.195539242778354,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}