{"id":"W2555297192","doi":"10.1136/annrheumdis-2016-eular.1398","title":"THU0430 Ixekizumab Provides Improvements through 52 Weeks in Physical Function, Quality of Life, and Work Productivity in Biologic Disease-Modifying Antirheumatic Drug-Naive Patients with Active Psoriatic Arthritis","year":2016,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Psoriasis: Treatment and Pathogenesis","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Medicine; Psoriatic arthritis; Dactylitis; Ixekizumab; Adalimumab; Quality of life (healthcare); Enthesitis; BASDAI; Internal medicine; Dermatology Life Quality Index; Ankylosing spondylitis; Placebo; Psoriasis; Presenteeism; Physical therapy; Arthritis; Rheumatoid arthritis; Immunology; Disease; Absenteeism; Secukinumab; Alternative medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003698674,0.0003021277,0.00106523,0.0001589404,0.000182713,0.0003914025,0.0002377121,0.0004185199,0.002773381],"category_scores_gemma":[0.0004285241,0.0001798418,0.0007453084,0.0001381254,0.00015923,0.0003467409,0.0001488468,0.0008943131,0.0004397285],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001571468,"about_ca_system_score_gemma":0.0002253577,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000654319,"about_ca_topic_score_gemma":0.001621771,"domain_scores_codex":[0.9997978,0.00006095028,0.00002020162,0.00003012249,0.00002973339,0.00006133056],"domain_scores_gemma":[0.9998286,0.00003065709,0.0000442786,0.00001872012,0.00001357336,0.00006417737],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.2787274,0.02669556,0.01699653,0.001189643,0.001494451,0.0003483692,0.0002518465,0.001167588,0.08906384,0.0001205559,0.0040018,0.5799425],"study_design_scores_gemma":[0.1136492,0.4770532,0.3768195,0.0002188441,0.002298924,0.001310318,0.0003915043,0.003674839,0.01815854,0.0003469824,0.005977564,0.0001006479],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954887,0.002827285,0.000145831,0.0001812502,0.00008553384,0.00004848405,0.0001447809,0.00006236343,0.001015653],"genre_scores_gemma":[0.9973085,0.000820813,0.0002318497,0.0001565835,0.00005804308,0.00002789975,0.000170129,0.000005418267,0.00122089],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002773381,"threshold_uncertainty_score":0.00927788,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02890524886302692,"score_gpt":0.2673986003624654,"score_spread":0.2384933514994385,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}