{"id":"W2555335642","doi":"10.1371/journal.pgen.1006452","title":"Functional Genomic Analysis of Candida albicans Adherence Reveals a Key Role for the Arp2/3 Complex in Cell Wall Remodelling and Biofilm Formation","year":2016,"lang":"en","type":"article","venue":"PLoS Genetics","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Genome Canada","keywords":"Biofilm; Candida albicans; Biology; Corpus albicans; Microbiology; Cell biology; Actin cytoskeleton; Extracellular matrix; Cell wall; Endocytosis; Cell; Cytoskeleton; Genetics; Bacteria","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001074443,0.0005350036,0.0003324096,0.0005663367,0.0001870222,0.000309955,0.0003698007,0.0002967344,0.001378349],"category_scores_gemma":[0.0002066574,0.0001957928,0.0005390273,0.0005683526,0.0002188326,0.00009055768,0.0002968515,0.000785628,0.0006135266],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004147328,"about_ca_system_score_gemma":0.0003513262,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002529575,"about_ca_topic_score_gemma":0.003090055,"domain_scores_codex":[0.999833,0.00001191339,0.00001937303,0.00003764385,0.00006450439,0.00003351845],"domain_scores_gemma":[0.9997993,0.00006142748,0.00005862804,0.00002077754,0.00002453106,0.00003527628],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005704506,0.00001935496,0.0002570873,0.00002611895,0.000003731267,0.00005203317,0.000009742455,0.00006150496,0.9983547,0.00003251815,0.00002860887,0.001097584],"study_design_scores_gemma":[0.00002359745,0.0002195276,0.04015719,0.00002128683,0.00005974483,0.0006592558,0.00007596329,0.002106379,0.9530041,0.00007306788,0.00357805,0.00002179546],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9849689,0.0008560475,0.005654396,0.0001403679,0.00002518238,0.00007551297,0.006740055,0.000223951,0.001315525],"genre_scores_gemma":[0.9639982,0.0008664911,0.01231047,0.0001783225,0.00001314611,0.00008765917,0.0191193,0.0001798829,0.003246513],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002529575,"threshold_uncertainty_score":0.005029678,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05801882622323079,"score_gpt":0.2671791892986657,"score_spread":0.209160363075435,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}