{"id":"W2555357529","doi":"10.1016/j.jmoldx.2016.07.011","title":"Validation of a Gene Expression Test for Mesothelioma Prognosis in Formalin-Fixed Paraffin-Embedded Tissues","year":2016,"lang":"en","type":"article","venue":"Journal of Molecular Diagnostics","topic":"Occupational and environmental lung diseases","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Institute for Occupational Safety and Health; National Cancer Institute; Medical Center, University of Pittsburgh; Centers for Disease Control and Prevention; University of Pennsylvania; York University; Castle Biosciences; University of Pittsburgh; Brigham and Women's Hospital","keywords":"Mesothelioma; Pathology; Gene; Immunohistochemistry; Biology; Computational biology; Medicine; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001875256,0.0003728762,0.000395746,0.001390332,0.00044982,0.000612235,0.0004313481,0.0006492479,0.001372153],"category_scores_gemma":[0.001574533,0.0002056289,0.0003725924,0.0008067579,0.0006173013,0.0004124531,0.0003350299,0.0003488962,0.0005550428],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002372151,"about_ca_system_score_gemma":0.0003502056,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006443147,"about_ca_topic_score_gemma":0.0008817271,"domain_scores_codex":[0.9989637,0.0002158235,0.0001096631,0.000257328,0.00030731,0.0001461005],"domain_scores_gemma":[0.9987252,0.0004876171,0.0001562667,0.0001419518,0.0004103149,0.00007856625],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001542228,0.0003136105,0.2748143,0.000137296,0.0001690178,0.0002782248,0.0001961045,0.0004158779,0.704842,0.0001627134,0.0002749214,0.01685369],"study_design_scores_gemma":[0.0001575394,0.002928628,0.6109444,0.0000590538,0.0006071037,0.002538945,0.0006493413,0.009599118,0.3685688,0.0004005717,0.003510214,0.00003628089],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9906312,0.0008609333,0.005911992,0.0001331049,0.00005736472,0.0001028152,0.0006984795,0.00008552047,0.00151865],"genre_scores_gemma":[0.9911919,0.0002651767,0.006038173,0.00006866439,0.00002931232,0.0001279985,0.00135565,0.00001427863,0.0009088313],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001875256,"threshold_uncertainty_score":0.009917378,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01208785026328729,"score_gpt":0.2754146121277457,"score_spread":0.2633267618644584,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}