{"id":"W2555628542","doi":"10.1182/blood.v116.21.2767.2767","title":"Lack of IL-7 Receptor Alpha Chain (CD127) Expression In T Cells Is a Hallmark of T-Cell Immunodeficiency In Schimke Immuno-Osseous Dysplasia (SIOD)","year":2010,"lang":"en","type":"article","venue":"Blood","topic":"Immunodeficiency and Autoimmune Disorders","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Children's & Women's Health Centre of British Columbia; University of British Columbia","funders":"","keywords":"Interleukin-7 receptor; Common gamma chain; Biology; Immunodeficiency; Immunology; Severe combined immunodeficiency; Receptor; T cell; Molecular biology; IL-2 receptor; Immune system; Genetics; Gene; Interleukin 10","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008005678,0.0002856614,0.0001718279,0.0004704483,0.0001698167,0.0001843123,0.0001215581,0.0002588898,0.002042379],"category_scores_gemma":[0.00018497,0.0001115402,0.0001163123,0.0001389187,0.0002459431,0.00008750517,0.0001691046,0.0002226822,0.0003228047],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000823227,"about_ca_system_score_gemma":0.00007019762,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004144929,"about_ca_topic_score_gemma":0.0005451976,"domain_scores_codex":[0.9998815,0.00001221631,0.00001678383,0.00002148747,0.0000382547,0.00002973203],"domain_scores_gemma":[0.999854,0.00002380886,0.00003428937,0.00001252643,0.00001947309,0.00005596612],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0002323474,0.00004026153,0.01912242,0.00005044205,0.00001619168,0.002411173,0.00008017437,0.00004881631,0.975199,0.00006884571,0.0000978004,0.002632529],"study_design_scores_gemma":[0.0001189365,0.001750015,0.5965717,0.00005434846,0.0001438299,0.06308162,0.0007040533,0.002546756,0.3292779,0.0003547957,0.005372459,0.00002361937],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998679,0.000202435,0.0002282073,0.00001459924,0.000003955675,0.000007750924,0.00009689741,0.00001686611,0.0007502151],"genre_scores_gemma":[0.9991574,0.00008487666,0.0001846431,0.00001306977,0.000004901677,0.000009031572,0.0001458113,0.000004829957,0.0003954492],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002042379,"threshold_uncertainty_score":0.00683248,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00761097727388331,"score_gpt":0.2231500136323792,"score_spread":0.2155390363584959,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}