{"id":"W2555924858","doi":"10.1053/j.gastro.2016.11.004","title":"No Difference Between Latiglutenase and Placebo in Reducing Villous Atrophy or Improving Symptoms in Patients With Symptomatic Celiac Disease","year":2016,"lang":"en","type":"article","venue":"Gastroenterology","topic":"Celiac Disease Research and Management","field":"Medicine","cited_by":135,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"University of Alberta; University of Colorado Denver; NorthShore University HealthSystem; McMaster University; Rush University; Thomas Jefferson University; Kaiser Permanente","keywords":"Medicine; Gastroenterology; Villous atrophy; Placebo; Internal medicine; Duodenum; Intraepithelial lymphocyte; Tissue transglutaminase; Biopsy; Atrophy; Ingestion; Gluten; Coeliac disease; Gluten free; Disease; Pathology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001197825,0.0005317078,0.003201914,0.0003137618,0.0002738271,0.0005311476,0.000439014,0.001483469,0.004802808],"category_scores_gemma":[0.002176304,0.0003635249,0.001503147,0.000284694,0.0005996613,0.001013761,0.0002654489,0.001586485,0.0003513703],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004056332,"about_ca_system_score_gemma":0.0004683129,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006925892,"about_ca_topic_score_gemma":0.001629769,"domain_scores_codex":[0.999456,0.0003057087,0.00007601081,0.00005051672,0.00004221715,0.00006954022],"domain_scores_gemma":[0.9985554,0.0007158601,0.0001615516,0.00006355367,0.00007180918,0.0004319623],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9421078,0.001823557,0.002084945,0.001475572,0.001593127,0.0001745086,0.00008761967,0.0001240706,0.006067722,0.0001446736,0.0004676988,0.0438487],"study_design_scores_gemma":[0.6757233,0.2663522,0.04724329,0.0003809547,0.004202835,0.000332328,0.0002732087,0.0005496192,0.001725344,0.0004091698,0.002758293,0.00004944625],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9687576,0.02511809,0.000263748,0.001286155,0.0007251922,0.0001995826,0.0003640271,0.00007459125,0.003210995],"genre_scores_gemma":[0.9930085,0.004546265,0.0003341033,0.000642529,0.0003147064,0.00007798523,0.0002693169,0.000005746036,0.000800769],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004802808,"threshold_uncertainty_score":0.01606697,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006106109119820193,"score_gpt":0.2246976776603195,"score_spread":0.2185915685404993,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}