{"id":"W2556298093","doi":"10.1136/annrheumdis-2016-eular.2402","title":"FRI0268 Safety and Efficacy of Subcutaneous Tocilizumab in Early Systemic Sclerosis: Results from The Open-Label Period of The Fasscinate Trial","year":2016,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Systemic Sclerosis and Related Diseases","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Western University","funders":"","keywords":"Medicine; Tocilizumab; Placebo; Internal medicine; Gastroenterology; Adverse effect; Randomized controlled trial; Open label; Clinical trial; Rheumatoid arthritis; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001711285,0.001081228,0.002154271,0.0003171273,0.0003553542,0.00136947,0.0006455978,0.001273229,0.00335118],"category_scores_gemma":[0.00169516,0.0003073499,0.002034064,0.000404695,0.0009041723,0.001026963,0.0003055985,0.003081648,0.001020946],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009465484,"about_ca_system_score_gemma":0.0008090652,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008934529,"about_ca_topic_score_gemma":0.001736097,"domain_scores_codex":[0.9992837,0.0003402424,0.00004000225,0.00009412716,0.00009048201,0.0001513457],"domain_scores_gemma":[0.9987979,0.0003577412,0.00029582,0.0001166842,0.00007063541,0.000361184],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.9224616,0.004596048,0.002242639,0.0005544574,0.001965772,0.0001405301,0.00008253653,0.0006202916,0.007378942,0.0002025584,0.001710968,0.0580437],"study_design_scores_gemma":[0.785501,0.1678801,0.03524705,0.0001301746,0.002456512,0.0003826774,0.0001191823,0.0009617345,0.002605234,0.0005169332,0.00412348,0.00007588414],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9855399,0.009782727,0.00025845,0.0006637573,0.0001937226,0.0001845899,0.00128669,0.00007744182,0.00201263],"genre_scores_gemma":[0.9935688,0.002329562,0.0003040131,0.0005369517,0.0003171198,0.0002315476,0.00130176,0.00001683095,0.001393502],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00335118,"threshold_uncertainty_score":0.0112108,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07402716531058635,"score_gpt":0.3010191833609156,"score_spread":0.2269920180503293,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}