{"id":"W2556470338","doi":"10.1182/blood.v108.11.368.368","title":"A Chemical Biology Screen Identifies Glucocorticoids as Inhibitors of C-Maf and C-Maf-Dependent Transactivation of Cyclin D2.","year":2006,"lang":"en","type":"article","venue":"Blood","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Mount Sinai Hospital; Princess Margaret Cancer Centre; Ontario Institute for Cancer Research","funders":"","keywords":"Transactivation; Cyclin D2; Cyclin D1; Cyclin; Biology; Cancer research; Cyclin D3; Molecular biology; Cell cycle; Cell; Biochemistry; Transcription factor; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002048094,0.0008313836,0.0006156417,0.001032611,0.0002925996,0.0003426689,0.0003969657,0.0004828456,0.002638439],"category_scores_gemma":[0.0002352352,0.0002484055,0.0006415271,0.0007150287,0.0001861915,0.0001652176,0.0002486247,0.0005417456,0.0007440691],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005632989,"about_ca_system_score_gemma":0.0005025726,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001895362,"about_ca_topic_score_gemma":0.007615088,"domain_scores_codex":[0.9998116,0.00002391957,0.00001176172,0.00003269848,0.0000841647,0.00003590075],"domain_scores_gemma":[0.9998291,0.00004480509,0.00003288318,0.00001017402,0.00004344614,0.00003951751],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002751434,0.0002971777,0.0007870006,0.0004909707,0.00007885337,0.000321693,0.00002392215,0.0007209245,0.9780629,0.0001825614,0.001205924,0.01755291],"study_design_scores_gemma":[0.0005662026,0.007079106,0.0097587,0.0001002788,0.0004367931,0.001477614,0.00007098549,0.002112843,0.9522001,0.000178351,0.02595685,0.00006211004],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9109644,0.0432258,0.00983991,0.001363162,0.0003488957,0.001202952,0.0128843,0.0008216705,0.01934892],"genre_scores_gemma":[0.9363458,0.02752887,0.01052566,0.0008943197,0.0000788449,0.0003796115,0.01029475,0.0000730867,0.01387894],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002638439,"threshold_uncertainty_score":0.008826435,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01181211805639537,"score_gpt":0.2817117927313165,"score_spread":0.2698996746749212,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}