{"id":"W2556538872","doi":"10.1139/apnm-2016-0346","title":"Inhibition of the gut enzyme intestinal alkaline phosphatase may explain how aspartame promotes glucose intolerance and obesity in mice","year":2016,"lang":"en","type":"article","venue":"Applied Physiology Nutrition and Metabolism","topic":"Diet and metabolism studies","field":"Medicine","cited_by":69,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases","keywords":"Aspartame; Alkaline phosphatase; Endocrinology; Internal medicine; Chemistry; Endogeny; Obesity; Enzyme; Phenylalanine; Metabolic syndrome; Medicine; Biochemistry; Amino acid","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003361289,0.0007892013,0.0006050178,0.0005902028,0.0002158747,0.0006416366,0.0004730212,0.0008474563,0.001603044],"category_scores_gemma":[0.0002279133,0.0004083751,0.001157129,0.0003144101,0.0004978027,0.0006442242,0.0004462977,0.002260208,0.0004649402],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004038358,"about_ca_system_score_gemma":0.0002976005,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005555649,"about_ca_topic_score_gemma":0.0008050557,"domain_scores_codex":[0.9996871,0.00004926705,0.00003398215,0.00006967474,0.0000801618,0.00007989117],"domain_scores_gemma":[0.9997806,0.00001528821,0.00008998397,0.00002676022,0.00001879037,0.0000685206],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001900629,0.0003405044,0.002273892,0.0003465233,0.00009720678,0.0004993703,0.00004634653,0.0001423315,0.9863697,0.001019679,0.0004441769,0.006519583],"study_design_scores_gemma":[0.0006218468,0.00411227,0.04806221,0.0001381062,0.0005014569,0.002498445,0.0002775491,0.005875577,0.9184743,0.002254934,0.01711979,0.00006365373],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9560634,0.01370949,0.01986947,0.003068111,0.0005785998,0.0001565203,0.001087051,0.0005995345,0.004867787],"genre_scores_gemma":[0.981978,0.006169497,0.00486332,0.0007627049,0.00007710058,0.0001857774,0.0006529842,0.00005926703,0.005251294],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001603044,"threshold_uncertainty_score":0.005362689,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01307716710922503,"score_gpt":0.2385484407613056,"score_spread":0.2254712736520806,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}