{"id":"W2556664795","doi":"10.1016/j.nantod.2016.10.005","title":"Emerging understanding of the protein corona at the nano-bio interfaces","year":2016,"lang":"en","type":"article","venue":"Nano Today","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":239,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval","funders":"National Institutes of Health; National Research Foundation of Korea; U.S. Department of Defense","keywords":"Nanomedicine; Biodistribution; Corona (planetary geology); Nanotechnology; Biomolecule; Nanoparticle; Nanotoxicology; Chemistry; Biophysics; Materials science; Biology; Biochemistry; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0006930295,0.0001372463,0.0001505093,0.00003109393,0.0002992101,0.00003715276,0.0005605326,0.00005176375,0.001229159],"category_scores_gemma":[0.0001401779,0.00005863931,0.00007197497,0.000180037,0.0004011939,0.0001818368,0.0003648297,0.00004996388,0.0002997314],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003185078,"about_ca_system_score_gemma":0.00007422391,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004972015,"about_ca_topic_score_gemma":0.000121681,"domain_scores_codex":[0.9985012,0.0002060058,0.0002911475,0.0002647149,0.0004012937,0.0003356675],"domain_scores_gemma":[0.9989353,0.0002057915,0.0002023843,0.0005628497,0.0000503541,0.00004334656],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005512331,0.00002167167,0.0005374852,0.00001265243,0.000006152916,9.232887e-7,0.0003536274,0.00001739539,0.9954258,0.001626715,0.001292114,0.0006503508],"study_design_scores_gemma":[0.0003791922,0.00004554735,0.0001194658,0.0001860979,0.00001332773,0.000003328,0.0002430748,0.00002104472,0.9954742,0.0009502635,0.002457949,0.0001065794],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9933751,0.000174059,0.0005796665,0.003753828,0.0009706913,0.000476198,0.00002421981,0.00004935311,0.0005969268],"genre_scores_gemma":[0.9956195,0.00000427977,0.0001129037,0.0001044411,0.00006265337,0.00003029094,2.232538e-7,0.00001730817,0.004048342],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003649387,"threshold_uncertainty_score":0.9996839,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02510973083252308,"score_gpt":0.2440340859139457,"score_spread":0.2189243550814227,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}