{"id":"W2556823464","doi":"10.1182/blood.v120.21.1629.1629","title":"Pharmacokinetics (PK), Safety and Overall Response Rate (ORR) Achieved with Subcutaneous (SC) Administration of Rituximab in Combination with Chemotherapy Were Comparable to Those Achieved with Intravenous (IV) Administration in Patients (pts) with Follicular Lymphoma (FL) in the First-Line Setting: Stage 1 Results of the Phase III SABRINA Study (BO22334)","year":2012,"lang":"en","type":"article","venue":"Blood","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen Elizabeth II Health Sciences Centre","funders":"","keywords":"Medicine; Rituximab; Dosing; Pharmacokinetics; Clinical endpoint; Chemotherapy; Internal medicine; Phases of clinical research; Gastroenterology; Urology; Pharmacology; Surgery; Randomized controlled trial; Lymphoma","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00096502,0.0004163607,0.001333655,0.000202429,0.0001443438,0.0006477531,0.0002855778,0.0005231231,0.002231656],"category_scores_gemma":[0.001465525,0.0002989165,0.0008482472,0.0003056046,0.000310844,0.0004314038,0.0001748328,0.00202671,0.0005236594],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003850227,"about_ca_system_score_gemma":0.0004551885,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004710963,"about_ca_topic_score_gemma":0.0008051429,"domain_scores_codex":[0.9995325,0.0002675987,0.00002493748,0.00005890422,0.0000634369,0.00005273105],"domain_scores_gemma":[0.9992608,0.0002280913,0.0002394015,0.00008383043,0.00004096212,0.000146807],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.4133743,0.0183193,0.01659705,0.0009840988,0.001825529,0.0002323127,0.0004097853,0.00486347,0.2207576,0.0001914544,0.003794639,0.3186505],"study_design_scores_gemma":[0.1181446,0.6527854,0.1588557,0.00009815686,0.002177401,0.001237458,0.0001648677,0.008410599,0.04982001,0.0002971096,0.007926125,0.00008259679],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9948651,0.001776517,0.0009236629,0.0001314456,0.00002464841,0.0002697914,0.000408534,0.0001088965,0.001491347],"genre_scores_gemma":[0.9977793,0.0003995458,0.0003985755,0.0001216211,0.00003164125,0.000118263,0.0004719479,0.0000293342,0.0006497776],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002231656,"threshold_uncertainty_score":0.007465661,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01180774793658254,"score_gpt":0.2692980065772841,"score_spread":0.2574902586407016,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}