{"id":"W2556884992","doi":"10.1038/srep36699","title":"Insights into a novel nuclear function for Fascin in the regulation of the amino-acid transporter SLC3A2","year":2016,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Cancer Foundation; University of Alberta; Université de Montréal; Hôpital Maisonneuve-Rosemont; University of Calgary; McGill University; Jewish General Hospital","funders":"Canadian Institutes of Health Research; Fondation du cancer du sein du Québec","keywords":"Fascin; H3K4me3; Biology; Cell biology; Histone; Epigenetics; Biochemistry; Gene expression; Gene; Promoter; Actin","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001154687,0.0001832991,0.0001563979,0.000113494,0.0001801297,0.000287957,0.0001246722,0.0001903767,0.001392959],"category_scores_gemma":[0.00007821568,0.00007602167,0.0002016911,0.00007016736,0.0002158333,0.0002441816,0.0001668264,0.0002258438,0.0002106724],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002706058,"about_ca_system_score_gemma":0.000204908,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005600559,"about_ca_topic_score_gemma":0.001161311,"domain_scores_codex":[0.9999446,0.000009304445,0.000003349229,0.00001686343,0.00001326032,0.00001269477],"domain_scores_gemma":[0.9999552,0.000006493091,0.000009930892,0.000005076452,0.000008465245,0.00001495103],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001306163,0.000009324905,0.001515259,0.00004027781,0.000006419055,0.0002264792,0.00003055575,0.0001381696,0.9942992,0.0008485825,0.00006078643,0.002694409],"study_design_scores_gemma":[0.00004326374,0.0002503258,0.08567738,0.00004715618,0.00006311434,0.002170566,0.0004563287,0.00862707,0.8837218,0.002236777,0.01668334,0.00002282974],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9789996,0.00551552,0.01079782,0.0007008477,0.00005682828,0.00001060662,0.0003689075,0.0001037572,0.003446099],"genre_scores_gemma":[0.994713,0.001286201,0.002081144,0.00009297705,0.00001234731,0.000006100594,0.0001568625,0.00001404988,0.001637162],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001392959,"threshold_uncertainty_score":0.004659891,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009487966946266494,"score_gpt":0.2005804236030158,"score_spread":0.1910924566567493,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}