{"id":"W2556978135","doi":"10.1182/blood.v126.23.4261.4261","title":"In Multiple Myeloma Progression Free and Overall Survival in the Relapsed Setting Remains Poor with Early Exposure to Novel Agents: Experience from a Real-World Cohort","year":2015,"lang":"en","type":"article","venue":"Blood","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; University of Alberta","funders":"","keywords":"Medicine; Lenalidomide; Multiple myeloma; Cohort; Bortezomib; Regimen; Internal medicine; Oncology; Progression-free survival; Refractory (planetary science); Maintenance therapy; Overall survival; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008035195,0.0002170538,0.0002997666,0.0003560149,0.000999865,0.0008614345,0.0003987487,0.0003651283,0.000967161],"category_scores_gemma":[0.001856121,0.0001359938,0.0002864092,0.0007039201,0.0003991722,0.0004262583,0.000686901,0.0005818143,0.0002517682],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001303192,"about_ca_system_score_gemma":0.00124958,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.02225183,"about_ca_topic_score_gemma":0.03376462,"domain_scores_codex":[0.9995253,0.0001204991,0.00003112621,0.0001052904,0.0001076808,0.0001101518],"domain_scores_gemma":[0.998894,0.0001520707,0.0003149786,0.0001028202,0.0002158734,0.0003202212],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002242476,0.000217699,0.9925122,0.00001245033,0.00002820406,0.001003217,0.0006817004,0.00004066422,0.0002601511,0.00002947262,0.000470434,0.004519572],"study_design_scores_gemma":[0.00006647993,0.001125864,0.9908186,0.00001912957,0.00004544021,0.003941021,0.002026286,0.0002401228,0.0002619334,0.00005910728,0.001382683,0.00001342816],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9992177,0.0001500667,0.00004693101,0.00006670624,0.000003285974,0.00001468181,0.0001525278,0.00000275659,0.0003453483],"genre_scores_gemma":[0.9992907,0.0001674836,0.00006369638,0.00006467182,0.00001300299,0.00001071522,0.0002269747,0.000002303842,0.000160443],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02225183,"threshold_uncertainty_score":0.04424465,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04123657981962096,"score_gpt":0.3169666778374186,"score_spread":0.2757300980177976,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}