{"id":"W2557010481","doi":"10.1182/blood.v124.21.800.800","title":"Ibrutinib Monotherapy in Relapsed/Refractory Follicular Lymphoma (FL): Preliminary Results of a Phase 2 Consortium (P2C) Trial","year":2014,"lang":"en","type":"article","venue":"Blood","topic":"Chronic Lymphocytic Leukemia Research","field":"Medicine","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto","funders":"","keywords":"Ibrutinib; Medicine; Internal medicine; Tolerability; Mantle cell lymphoma; Oncology; Bruton's tyrosine kinase; Follicular lymphoma; Clinical endpoint; Lymphoma; Clinical trial; Chronic lymphocytic leukemia; Adverse effect; Leukemia; Tyrosine kinase","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002695252,0.001287763,0.001149651,0.0002955432,0.0004068835,0.001130441,0.0007603423,0.001080004,0.002981753],"category_scores_gemma":[0.001004893,0.0002756318,0.0007990626,0.0004595713,0.0004806068,0.0006602483,0.0003487124,0.002351006,0.00081304],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001244242,"about_ca_system_score_gemma":0.001371395,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002361293,"about_ca_topic_score_gemma":0.005458847,"domain_scores_codex":[0.9994824,0.0002789791,0.00002401215,0.00006396369,0.00005506615,0.00009553866],"domain_scores_gemma":[0.9994117,0.0001210339,0.00008339397,0.00004363029,0.00007188502,0.0002684156],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.5643832,0.02822908,0.01415517,0.002281719,0.003395656,0.001075764,0.0007289673,0.003843158,0.05332255,0.0005208027,0.02987812,0.2981859],"study_design_scores_gemma":[0.7471581,0.1927407,0.03791404,0.0002402102,0.001357961,0.0009441067,0.0001616281,0.002160892,0.003551282,0.0003828217,0.01332144,0.00006696829],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.978584,0.009013851,0.0004183946,0.001778652,0.0001503672,0.001582104,0.002390502,0.0001946837,0.005887576],"genre_scores_gemma":[0.9833995,0.004176839,0.001402849,0.001964017,0.0002310677,0.001656058,0.004435863,0.00004390298,0.002689973],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002981753,"threshold_uncertainty_score":0.01425397,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02253585587394135,"score_gpt":0.3137643005637181,"score_spread":0.2912284446897768,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}