{"id":"W2557135000","doi":"10.1182/blood.v112.11.570.570","title":"Distinct Gab2-Mediated Signaling Pathways Are Essential for Myeloid or Lymphoid Transformation and Leukemogenesis by BCR-ABL","year":2008,"lang":"en","type":"article","venue":"Blood","topic":"Chronic Myeloid Leukemia Treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ontario Institute for Cancer Research","funders":"","keywords":"Chronic myelogenous leukemia; Cancer research; Biology; Leukemia; breakpoint cluster region; Myeloid; Tyrosine kinase; Dasatinib; Myeloid leukemia; Immunology; Signal transduction; Imatinib; Cell biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001732398,0.0008166318,0.0001951999,0.0003757884,0.0002266482,0.0004304793,0.0002740368,0.0002944994,0.00107212],"category_scores_gemma":[0.0001391818,0.0001960961,0.0002594591,0.0001667702,0.0002807362,0.0002996212,0.0006111513,0.000489139,0.0004671942],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003829377,"about_ca_system_score_gemma":0.0003061231,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005802949,"about_ca_topic_score_gemma":0.001670464,"domain_scores_codex":[0.9997873,0.0000415392,0.00002622671,0.0000286102,0.00006327409,0.00005304706],"domain_scores_gemma":[0.9998216,0.00001430048,0.0000669157,0.00001837804,0.00001387325,0.00006509593],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009298619,0.00001112658,0.0002931833,0.00002278277,0.000003338883,0.00005853686,0.000009401066,0.00005545305,0.9987721,0.0002155552,0.00001389035,0.0004516579],"study_design_scores_gemma":[0.00005269572,0.0002162633,0.01893991,0.00002028149,0.00003695023,0.0009792951,0.00007799398,0.001866114,0.9741508,0.0001833734,0.003466057,0.00001034211],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950821,0.00200779,0.001593805,0.00006478692,0.00001163721,0.00001993013,0.0003792127,0.0000651308,0.0007755639],"genre_scores_gemma":[0.9957392,0.0007618744,0.001342016,0.00003657478,0.000006363665,0.00003895876,0.0006974334,0.00002214572,0.001355499],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00107212,"threshold_uncertainty_score":0.00358659,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02127013365429725,"score_gpt":0.2350585023237531,"score_spread":0.2137883686694559,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}