{"id":"W2557167806","doi":"10.1021/acsomega.6b00178","title":"Small-Molecule Ice Recrystallization Inhibitors Improve the Post-Thaw Function of Hematopoietic Stem and Progenitor Cells","year":2016,"lang":"en","type":"article","venue":"ACS Omega","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Blood Services; University of Ottawa","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; Canadian Blood Services","keywords":"Cryopreservation; Cryoprotectant; Progenitor cell; Haematopoiesis; Stem cell; Dimethyl sulfoxide; Andrology; Transplantation; Recrystallization (geology); Cell biology; Hematopoietic stem cell; Chemistry; Biology; Internal medicine; Medicine; Embryo","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001745621,0.0003657903,0.0002059795,0.000222795,0.00008075497,0.0001717938,0.0002160732,0.0002084144,0.001947978],"category_scores_gemma":[0.0001087919,0.0001290486,0.0001954718,0.0001156387,0.00009047534,0.0002151356,0.00009682145,0.0004480178,0.0004577973],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001729996,"about_ca_system_score_gemma":0.0002177042,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006356636,"about_ca_topic_score_gemma":0.0009780597,"domain_scores_codex":[0.999923,0.000009064353,0.000006831655,0.00001556935,0.00002716568,0.00001838761],"domain_scores_gemma":[0.9999183,0.00002580282,0.00001804318,0.000006397154,0.00001792823,0.00001351465],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009091936,0.000020679,0.00004855881,0.00003890685,0.000003202358,0.00001502854,0.000007404797,0.00006469346,0.9973378,0.00003790914,0.00009366529,0.002241181],"study_design_scores_gemma":[0.00000768023,0.0001764399,0.00123788,0.000002965152,0.000006301242,0.00002867297,0.000005218476,0.0004160736,0.9967534,0.00001037551,0.001353009,0.000001846839],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9647027,0.009030375,0.01609431,0.0002605375,0.0001021362,0.0001385627,0.001335986,0.0006284121,0.007706941],"genre_scores_gemma":[0.9638109,0.007163136,0.0149082,0.0002224472,0.00002105617,0.0001579494,0.002001884,0.00009343631,0.01162105],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001947978,"threshold_uncertainty_score":0.006516635,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01417262462629911,"score_gpt":0.2206832619788852,"score_spread":0.2065106373525861,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}