{"id":"W2557178154","doi":"10.1097/tp.0000000000001559","title":"Effect of Ex Vivo–Expanded Recipient Regulatory T Cells on Hematopoietic Chimerism and Kidney Allograft Tolerance Across MHC Barriers in Cynomolgus Macaques","year":2016,"lang":"en","type":"article","venue":"Transplantation","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":67,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Center for Research Resources; National Institute of Allergy and Infectious Diseases; National Institutes of Health","keywords":"FOXP3; Immunosuppression; Immunology; Transplantation Chimera; Immune tolerance; Medicine; T cell; IL-2 receptor; Regulatory T cell; Haematopoiesis; Transplantation; Immune system; Stem cell; Biology; Internal medicine; Hematopoietic cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000273175,0.0002864737,0.0002495017,0.0002455623,0.0001481022,0.0002123465,0.000177856,0.0002501963,0.0008525959],"category_scores_gemma":[0.0001828186,0.00009460504,0.000186286,0.00005074024,0.0002351497,0.0001445713,0.0001736812,0.0004265708,0.0001558252],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001753101,"about_ca_system_score_gemma":0.0001661695,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005971094,"about_ca_topic_score_gemma":0.001207767,"domain_scores_codex":[0.9998347,0.00004203978,0.00001293598,0.00002914736,0.00002384569,0.00005733517],"domain_scores_gemma":[0.9998369,0.00002925936,0.00004045681,0.00002388047,0.0000154326,0.00005410685],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000809468,0.0002860654,0.0008316694,0.00005596636,0.00001162411,0.0001064381,0.00007698046,0.00008026541,0.9944899,0.00005867506,0.00004697924,0.003145917],"study_design_scores_gemma":[0.0002234874,0.01224825,0.02262037,0.00005223163,0.0001510106,0.001112788,0.0001486208,0.001728091,0.9572555,0.0001216024,0.004321517,0.00001667908],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9990824,0.0003688583,0.0002010527,0.00002137104,0.0000071068,0.00001130129,0.00003447307,0.00001556868,0.000257726],"genre_scores_gemma":[0.9984854,0.0002114146,0.000461855,0.00003357071,0.000008753545,0.00003218611,0.0001335788,0.00001059406,0.0006226046],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008525959,"threshold_uncertainty_score":0.002852201,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004340229349282832,"score_gpt":0.2295705976398473,"score_spread":0.2252303682905645,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}