{"id":"W2557367716","doi":"10.1016/j.antiviral.2016.11.019","title":"Assessment of the potential for host-targeted iminosugars UV-4 and UV-5 activity against filovirus infections in vitro and in vivo","year":2016,"lang":"en","type":"article","venue":"Antiviral Research","topic":"Viral Infections and Outbreaks Research","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":false,"ca_institutions":"Public Health Agency of Canada","funders":"National Institutes of Health; Public Health Agency of Canada; Emergent BioSolutions","keywords":"In vivo; In vitro; Host (biology); Virology; Microbiology; Biology; Chemistry; Biochemistry; Biotechnology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002968656,0.0004108311,0.0002088323,0.0001535901,0.0001542405,0.0002338351,0.0002738877,0.00027616,0.001713147],"category_scores_gemma":[0.0002031705,0.00009969912,0.0001985333,0.0001170031,0.0001799617,0.0001890821,0.00009383382,0.000408241,0.0001990009],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001680127,"about_ca_system_score_gemma":0.0001734505,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006563231,"about_ca_topic_score_gemma":0.0006508506,"domain_scores_codex":[0.9998692,0.00004600132,0.000008763812,0.00001803726,0.00002481829,0.00003307902],"domain_scores_gemma":[0.9998816,0.0000519555,0.00002076741,0.00001777561,0.0000134492,0.00001438029],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003859171,0.0000681194,0.0001129317,0.00004435346,0.000009084847,0.00002057043,0.0000199632,0.0002622982,0.9973308,0.0001157149,0.00003095945,0.001599384],"study_design_scores_gemma":[0.00001138882,0.0007405403,0.0003380299,0.000002067793,0.00001129927,0.00002440178,0.000009900431,0.0003270974,0.9981029,0.00001106357,0.0004196716,0.000001599301],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9952295,0.001133829,0.001495484,0.00003768735,0.00002001279,0.00003027622,0.0002024073,0.00004923492,0.001801557],"genre_scores_gemma":[0.9967068,0.0005391676,0.001233859,0.00001230162,0.000006846544,0.00002239402,0.0002423163,0.000008120646,0.001228189],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001713147,"threshold_uncertainty_score":0.005731106,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04746248677001807,"score_gpt":0.4019827718104963,"score_spread":0.3545202850404782,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}