{"id":"W2557367716","doi":"10.1016/j.antiviral.2016.11.019","title":"Assessment of the potential for host-targeted iminosugars UV-4 and UV-5 activity against filovirus infections in vitro and in vivo","year":2016,"lang":"en","type":"article","venue":"Antiviral Research","topic":"Viral Infections and Outbreaks Research","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":false,"ca_institutions":"Public Health Agency of Canada","funders":"National Institutes of Health; Public Health Agency of Canada; Emergent BioSolutions","keywords":"In vivo; In vitro; Host (biology); Virology; Microbiology; Biology; Chemistry; Biochemistry; Biotechnology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001387078,0.000117468,0.0002729577,0.0005581863,0.0001799545,0.00003371707,0.00008537382,0.0001196096,0.00001674932],"category_scores_gemma":[0.0006284974,0.00007048177,0.00007735127,0.0006522774,0.0004573003,0.0001948361,0.0002424067,0.0004694145,0.000001740713],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001503252,"about_ca_system_score_gemma":0.0002807353,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001240358,"about_ca_topic_score_gemma":0.0007025014,"domain_scores_codex":[0.9981651,0.0003278234,0.0002232481,0.0003253114,0.0004577975,0.0005007058],"domain_scores_gemma":[0.9988374,0.0005985938,0.00004127612,0.0002435919,0.0002079275,0.00007120273],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0003579486,0.0002885978,0.1604219,0.00006701865,0.00001939186,0.000009579457,0.00002874439,5.419722e-7,0.8198837,0.00006992155,0.0001065198,0.01874614],"study_design_scores_gemma":[0.002123992,0.000412465,0.6780331,0.0001160974,0.000006816391,0.000007422595,0.00006422053,0.001215514,0.3176881,0.0001079482,0.0001534064,0.00007090015],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956788,0.00004992828,0.0001391625,0.001556127,0.00005638651,0.001038477,0.00007695385,0.000009373352,0.001394748],"genre_scores_gemma":[0.9984117,0.0005160258,0.00009759027,0.00002550857,0.00004772953,0.0001081832,0.000001783405,0.00001626622,0.0007752154],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5176112,"threshold_uncertainty_score":0.2874163,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04746248677001807,"score_gpt":0.4019827718104963,"score_spread":0.3545202850404782,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}