{"id":"W2557419037","doi":"10.1182/blood.v118.21.3075.3075","title":"Treatment of Severe Relapsing-Remitting Multiple Sclerosis with High-Dose Immunosuppressive Therapy and Autologous Hematopoietic Cell Transplantation: Early Results of the HALT MS Clinical Trial (Immune Tolerance Network: ITN033AI)","year":2011,"lang":"en","type":"article","venue":"Blood","topic":"Multiple Sclerosis Research Studies","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Medicine; Multiple sclerosis; Expanded Disability Status Scale; Transplantation; Internal medicine; Clinical endpoint; Hematopoietic stem cell transplantation; Adverse effect; Clinical trial; Prednisone; Surgery; Oncology; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002137858,0.0006035704,0.001239315,0.0002711461,0.0002716654,0.0007620698,0.000527994,0.0009785574,0.001463621],"category_scores_gemma":[0.0006451849,0.0001801099,0.0009016151,0.000233199,0.0006217663,0.0004025157,0.0002844344,0.002115795,0.0002654448],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000374632,"about_ca_system_score_gemma":0.0008211307,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006093392,"about_ca_topic_score_gemma":0.0009873667,"domain_scores_codex":[0.9996189,0.0002435679,0.00001748025,0.0000262239,0.00003562809,0.00005809045],"domain_scores_gemma":[0.9995072,0.0001351169,0.00006100164,0.00003610941,0.00003274219,0.0002277549],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.7088845,0.03846848,0.003926316,0.0007696213,0.001116309,0.0003107756,0.000226281,0.00243047,0.02149261,0.0006595463,0.003392556,0.2183225],"study_design_scores_gemma":[0.4678747,0.5105404,0.01230676,0.0001115095,0.0004741212,0.0002737451,0.00005004651,0.002063798,0.003161678,0.0003025612,0.002818403,0.00002223848],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9909511,0.005156765,0.0003871934,0.0005317777,0.0001297007,0.0007254436,0.0002841277,0.00005853651,0.001775441],"genre_scores_gemma":[0.9906261,0.003048062,0.001539488,0.001053455,0.000222733,0.000806758,0.0009619508,0.00001519983,0.001726288],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002137858,"threshold_uncertainty_score":0.01130617,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09360182902522937,"score_gpt":0.291791312662789,"score_spread":0.1981894836375596,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}