{"id":"W2557439120","doi":"10.1182/blood.v116.21.870.870","title":"Therapeutic Potential for Toll-Like Receptor 2 Agonists In Pediatric Acute Lymphoblastic Leukemia (pre-B ALL): Induction of Apoptosis and Anti-ALL Immunogenicity","year":2010,"lang":"en","type":"article","venue":"Blood","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Children's Hospital","funders":"","keywords":"Immunology; Medicine; Leukemia; Minimal residual disease; Immunogenicity; Immune system; TLR9; Transplantation; Cancer research; Biology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002094481,0.0002681255,0.000221364,0.0001988457,0.00007503868,0.0002124168,0.0001381139,0.0002216665,0.001482834],"category_scores_gemma":[0.000104571,0.00007145853,0.000252249,0.0001148146,0.0001459872,0.0001752177,0.0001616024,0.0006660599,0.0002761068],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001197069,"about_ca_system_score_gemma":0.0001567465,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006538989,"about_ca_topic_score_gemma":0.0001219719,"domain_scores_codex":[0.9999305,0.00002398474,0.000004967831,0.000007781328,0.0000127833,0.00001997285],"domain_scores_gemma":[0.999956,0.00001116268,0.00001296759,0.000004167997,0.00000538138,0.00001035101],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003335833,0.001269313,0.001070797,0.0008360861,0.00004328931,0.0002805676,0.00005227856,0.0005022557,0.9174544,0.0006858625,0.0007453613,0.07372383],"study_design_scores_gemma":[0.001255354,0.0411545,0.009248727,0.00009432372,0.000266127,0.002494212,0.0001110835,0.001413162,0.9196843,0.0004176955,0.02384738,0.00001320237],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9650893,0.02656848,0.00383274,0.0006192261,0.0002197307,0.0001978852,0.0002230466,0.0001364395,0.003113244],"genre_scores_gemma":[0.9861795,0.009162332,0.002773357,0.0001874093,0.00007776318,0.0001434389,0.000223691,0.000008736378,0.001243763],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001482834,"threshold_uncertainty_score":0.004960597,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006792298349318342,"score_gpt":0.2273122158807968,"score_spread":0.2205199175314784,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}