{"id":"W2557616120","doi":"10.1182/blood.v126.23.384.384","title":"Proteomic Analysis of Reprograming of Mesenchymal Stem/Stromal Cells (MSC) Following Interferon Gamma Identifies Pathways That Are Upregulated in Suppression","year":2015,"lang":"en","type":"article","venue":"Blood","topic":"Immune cells in cancer","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; CancerCare Manitoba","funders":"","keywords":"Mesenchymal stem cell; Downregulation and upregulation; Stromal cell; Proteome; Biology; Cancer research; Interferon gamma; Stem cell; Immunology; Molecular biology; Chemistry; Cytokine; Cell biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001173759,0.0002546335,0.0002288905,0.0003353434,0.0001493185,0.000230847,0.00007441999,0.0001412203,0.000848006],"category_scores_gemma":[0.00009772155,0.00008655047,0.0002380689,0.0003253471,0.0001219692,0.0001169812,0.0001592438,0.0002155135,0.0003687562],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001199655,"about_ca_system_score_gemma":0.000130684,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002987934,"about_ca_topic_score_gemma":0.0004181628,"domain_scores_codex":[0.9998982,0.00001108303,0.000009739602,0.00002016349,0.00004134346,0.00001939433],"domain_scores_gemma":[0.9999242,0.00001064894,0.00002143346,0.000007227603,0.00001854863,0.00001793774],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000051426,0.000004009672,0.0003169719,0.00001524624,0.000002722948,0.00002895721,0.000007369741,0.0000108935,0.9991809,0.000007670586,0.000008414566,0.0003653185],"study_design_scores_gemma":[0.000005366424,0.0001828497,0.04424933,0.000009641259,0.0000335833,0.0004078718,0.00009298513,0.0006103982,0.9525671,0.00003315857,0.001802901,0.000004842182],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9924113,0.001034139,0.003240578,0.00005294035,0.00002920492,0.0000375916,0.001886419,0.00004088795,0.001267075],"genre_scores_gemma":[0.9882491,0.001366979,0.004524544,0.0000969383,0.00001525904,0.00008414399,0.003221912,0.00002161441,0.002419432],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000848006,"threshold_uncertainty_score":0.002836823,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03123578931583127,"score_gpt":0.2456097247013094,"score_spread":0.2143739353854782,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}