{"id":"W2557753042","doi":"10.1107/s2053273314098817","title":"Structural determinants of ssDNA- and HIV-1 Vif-binding in APOBEC3F","year":2014,"lang":"en","type":"article","venue":"Acta Crystallographica Section A Foundations and Advances","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"APOBEC3G; Mutagenesis; DNA; Human immunodeficiency virus (HIV); Cytosine; Biology; Single-domain antibody; Biophysics; Plasma protein binding; Cell biology; Chemistry; Genetics; Mutation; Virology; Cytidine deaminase; Antibody; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001741422,0.0002067327,0.0002731455,0.0001297453,0.0003533535,0.000316551,0.0003480125,0.0003864609,0.001576182],"category_scores_gemma":[0.0003103006,0.0001256244,0.0001897151,0.0001532631,0.0002988783,0.0001944915,0.0001807764,0.0005370396,0.0003291841],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006766185,"about_ca_system_score_gemma":0.0005350314,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007457223,"about_ca_topic_score_gemma":0.009460866,"domain_scores_codex":[0.9998666,0.00002062436,0.000005568165,0.00001822273,0.00004662386,0.00004230722],"domain_scores_gemma":[0.9998356,0.00005031767,0.00002861196,0.000006499105,0.00002506547,0.00005389964],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008625066,0.0002227263,0.007716686,0.000107199,0.00003313203,0.0009737642,0.0001395466,0.003428261,0.9757738,0.002448855,0.0007131648,0.007580404],"study_design_scores_gemma":[0.0003201565,0.001078918,0.08735504,0.0000649986,0.0001143356,0.002152486,0.0004965173,0.04322841,0.8540639,0.002087627,0.008928009,0.0001095339],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971437,0.0005191844,0.0009886136,0.00006874292,0.00001114872,0.0000103022,0.00007814453,0.00002836568,0.001151834],"genre_scores_gemma":[0.9986414,0.0001067936,0.0006804546,0.00003442439,0.000003348031,0.000003986694,0.0001199514,0.000006175902,0.0004034648],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007457223,"threshold_uncertainty_score":0.01482767,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01097447355311805,"score_gpt":0.2729374326003965,"score_spread":0.2619629590472785,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}