{"id":"W2557914993","doi":"10.1182/blood.v126.23.458.458","title":"Comparison of Efficacy and Safety Results in 103 Treatment-Naïve Acute Myeloid Leukemia (TN-AML) Patients Not Candidates for Intensive Chemotherapy Using 5-Day and 10-Day Regimens of Guadecitabine (SGI-110), a Novel Hypomethylating Agent (HMA)","year":2015,"lang":"en","type":"article","venue":"Blood","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Medicine; Tolerability; Regimen; Internal medicine; Chemotherapy regimen; Clinical endpoint; Chemotherapy; Neutropenia; Gastroenterology; Surgery; Adverse effect; Clinical trial","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000827783,0.0004734017,0.001114818,0.0002569209,0.0002963883,0.0004477702,0.0002472234,0.0005575473,0.001702915],"category_scores_gemma":[0.0007174993,0.000227847,0.0007075031,0.0002489084,0.0004964686,0.0004051991,0.0002626064,0.0009936431,0.0003431637],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004588718,"about_ca_system_score_gemma":0.000436838,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003603736,"about_ca_topic_score_gemma":0.0005152114,"domain_scores_codex":[0.9995977,0.000144882,0.0000360275,0.00009716876,0.00004614347,0.00007816088],"domain_scores_gemma":[0.999271,0.0002023196,0.0001341253,0.0000702741,0.00004388005,0.0002784315],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.637754,0.06709785,0.06942705,0.0003066752,0.0009880529,0.0004788492,0.0003949302,0.004071951,0.101715,0.0002085329,0.001008318,0.1165488],"study_design_scores_gemma":[0.0694675,0.8208492,0.09656516,0.00001535003,0.0004400811,0.0004383374,0.00008479304,0.001956999,0.008985462,0.0001332382,0.001030787,0.00003307089],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.999357,0.0001370368,0.0000648788,0.00001573417,0.000006268142,0.00009847503,0.00007924373,0.000005509988,0.0002358057],"genre_scores_gemma":[0.9985874,0.0001089637,0.000199553,0.00007439711,0.00002543476,0.0001811266,0.0005395771,0.000003551529,0.0002799317],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001702915,"threshold_uncertainty_score":0.005696774,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06681648524867487,"score_gpt":0.3531600435505407,"score_spread":0.2863435583018659,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}