{"id":"W2558013362","doi":"10.1182/blood.v104.11.4023.4023","title":"A Post-Marketing Surveillance Study of the Safety and Efficiacy of Refacto® (Moroctocog Alfa, B-Domain Deleted Recombinant Factor VIII) (St. Louis-Derived Active Substance in the Treatment and Prevension of Bleeding Episodes in Hemophilia a Patients.","year":2004,"lang":"en","type":"article","venue":"Blood","topic":"Hemophilia Treatment and Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Women's Health Research Institute","funders":"","keywords":"Medicine; Adverse effect; Dosing; Concomitant; Regimen; Postmarketing surveillance; Internal medicine; Surgery; Clinical endpoint; Clinical trial","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004031371,0.0009195507,0.001124213,0.0004128154,0.0004742615,0.0006401733,0.0003584807,0.001015832,0.001960925],"category_scores_gemma":[0.004351814,0.0004329403,0.0008766752,0.0003103343,0.0006831439,0.0007603854,0.0002558217,0.001650674,0.0004312659],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004553279,"about_ca_system_score_gemma":0.0004657175,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006479825,"about_ca_topic_score_gemma":0.0006912806,"domain_scores_codex":[0.9981851,0.001135283,0.0001060054,0.0002060766,0.0002252207,0.0001422843],"domain_scores_gemma":[0.9941896,0.001788707,0.001941679,0.0003907602,0.0005656755,0.00112363],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.7286997,0.08408561,0.09125927,0.0004872397,0.001512872,0.0002989478,0.0005790705,0.0004418019,0.02056691,0.0001420184,0.001401971,0.07052454],"study_design_scores_gemma":[0.0858901,0.728841,0.1779568,0.00002201296,0.0006283501,0.0003110764,0.00009262695,0.001079696,0.00364983,0.00004198069,0.001453835,0.00003275008],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982622,0.0004658148,0.0001752817,0.00005833616,0.00003304267,0.0003154844,0.0002178098,0.00001657593,0.0004553761],"genre_scores_gemma":[0.9978446,0.0002011824,0.0003216526,0.0001718478,0.0001757891,0.0002090727,0.00049842,0.00000583065,0.0005715898],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004031371,"threshold_uncertainty_score":0.02132022,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01520907367404116,"score_gpt":0.2644722875788598,"score_spread":0.2492632139048186,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}