{"id":"W2558150217","doi":"10.14283/jfa.2016.112","title":"EFFECT OF LOW-DOSE RAPAMYCIN ON SENESCENCE MARKERS AND PHYSICAL FUNCTIONING IN OLDER ADULTS WITH CORONARY ARTERY DISEASE: RESULTS OF A PILOT STUDY","year":2016,"lang":"en","type":"article","venue":"The Journal of Frailty & Aging","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":61,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institute of Nutrition, Metabolism and Diabetes","funders":"","keywords":"Medicine; Senescence; Coronary artery disease; Internal medicine; Adipose tissue; Interleukin 6; Endocrinology; Inflammation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009626036,0.0008141983,0.002066382,0.0002502939,0.0005356902,0.0005049038,0.000432168,0.0008736794,0.001673007],"category_scores_gemma":[0.001007916,0.000311306,0.0009251781,0.0002530982,0.0007405857,0.0006724163,0.0004944974,0.001515157,0.0002605004],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003064274,"about_ca_system_score_gemma":0.0007761617,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001430706,"about_ca_topic_score_gemma":0.00238323,"domain_scores_codex":[0.9996083,0.0001748744,0.00003838771,0.00006366087,0.00003380036,0.00008089355],"domain_scores_gemma":[0.9992964,0.000193183,0.0000905044,0.00007771253,0.00006069853,0.0002813777],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.7477089,0.1022329,0.02099731,0.0006291978,0.001480223,0.0001904876,0.0004283618,0.0004701283,0.05951526,0.00007067264,0.0007125415,0.06556406],"study_design_scores_gemma":[0.05011417,0.8137566,0.1275327,0.00004174212,0.001445682,0.0001192019,0.0003320086,0.0005036113,0.005297576,0.00007890019,0.0007379247,0.00004001873],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9990281,0.0004644261,0.00006134282,0.00004982044,0.00002037351,0.0001058876,0.00009989002,0.000009979704,0.0001602053],"genre_scores_gemma":[0.9978591,0.0005436631,0.000474718,0.0001270618,0.00007588509,0.0002703869,0.0002212677,0.000005761332,0.0004221819],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002066382,"threshold_uncertainty_score":0.005596757,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01169253811883135,"score_gpt":0.2595634256398094,"score_spread":0.2478708875209781,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}