{"id":"W2558377736","doi":"10.3899/jrheum.160287","title":"Five-year Efficacy and Safety of Tocilizumab Monotherapy in Patients with Rheumatoid Arthritis Who Were Methotrexate- and Biologic-naive or Free of Methotrexate for 6 Months: the AMBITION Study","year":2016,"lang":"en","type":"article","venue":"The Journal of Rheumatology","topic":"Rheumatoid Arthritis Research and Therapies","field":"Medicine","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Methotrexate; Tocilizumab; Rheumatoid arthritis; Antirheumatic Agents; Internal medicine; Biologic Agents; Arthritis; Surgery","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003279105,0.0005707513,0.001242157,0.0004417001,0.0004223366,0.0007644891,0.0003435824,0.0008688627,0.0009341194],"category_scores_gemma":[0.001701153,0.0002380548,0.00120777,0.000327215,0.000346032,0.0005728364,0.0003428872,0.001127821,0.0003060134],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003154309,"about_ca_system_score_gemma":0.0003555999,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003495294,"about_ca_topic_score_gemma":0.0006662211,"domain_scores_codex":[0.9989815,0.0004727694,0.000128762,0.0001087362,0.0002035438,0.0001047],"domain_scores_gemma":[0.9980051,0.0003803324,0.0008657014,0.000134616,0.0001597485,0.0004544058],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.4527628,0.01358496,0.4228163,0.001056097,0.007778123,0.0005863413,0.0005767219,0.001312599,0.01371406,0.0001158468,0.001721564,0.08397461],"study_design_scores_gemma":[0.0588911,0.2974586,0.6312765,0.0001091495,0.004560902,0.00119636,0.0001775192,0.001412487,0.002200547,0.00009701941,0.002525297,0.00009447372],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965382,0.002076527,0.0001157681,0.00005851415,0.00001800103,0.00009939478,0.000315216,0.00001364563,0.0007647016],"genre_scores_gemma":[0.9980476,0.0004259328,0.0001803496,0.000158196,0.00006748529,0.00008738703,0.0007086898,0.000002472191,0.0003219095],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003279105,"threshold_uncertainty_score":0.01734179,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01458591517229623,"score_gpt":0.2775176004651536,"score_spread":0.2629316852928574,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}