{"id":"W2558389544","doi":"10.1016/j.ejca.2016.09.004","title":"ENGOT-ov-6/TRINOVA-2: Randomised, double-blind, phase 3 study of pegylated liposomal doxorubicin plus trebananib or placebo in women with recurrent partially platinum-sensitive or resistant ovarian cancer","year":2016,"lang":"en","type":"article","venue":"European Journal of Cancer","topic":"Angiogenesis and VEGF in Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":80,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Princess Margaret Cancer Centre","funders":"NIHR Biomedical Research Centre, Royal Marsden NHS Foundation Trust/Institute of Cancer Research; Amgen","keywords":"Medicine; Placebo; Hazard ratio; Adverse effect; Internal medicine; Clinical endpoint; Surgery; Gastroenterology; Urology; Randomized controlled trial; Confidence interval; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001127505,0.001608133,0.003061269,0.000592438,0.000332733,0.0009513652,0.001003327,0.001775875,0.008460999],"category_scores_gemma":[0.001151735,0.000899174,0.001336197,0.000400626,0.001210185,0.001276508,0.0004155189,0.003277567,0.001640493],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005556873,"about_ca_system_score_gemma":0.0009585599,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001149766,"about_ca_topic_score_gemma":0.002538079,"domain_scores_codex":[0.9996916,0.0001461768,0.00001504415,0.0000592753,0.00001852726,0.00006943725],"domain_scores_gemma":[0.9995487,0.0001211851,0.00006732343,0.0000400586,0.00002040519,0.0002022815],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9665607,0.006137818,0.0003154506,0.0006463437,0.0005020386,0.00004073291,0.00007229055,0.0005158682,0.005561482,0.0001650437,0.0008347977,0.01864752],"study_design_scores_gemma":[0.9392965,0.05810927,0.0008634198,0.00002139697,0.0001673201,0.00002808303,0.00002339385,0.0003170435,0.0004080987,0.000124064,0.0006251551,0.0000162875],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9823197,0.005074683,0.00131847,0.0009370127,0.0007264549,0.004058652,0.002088481,0.0004231692,0.003053404],"genre_scores_gemma":[0.9763252,0.004234266,0.002155086,0.001339793,0.0003754215,0.004678483,0.002059529,0.000101822,0.008730468],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008460999,"threshold_uncertainty_score":0.02830487,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03384322118829779,"score_gpt":0.3135375361376028,"score_spread":0.279694314949305,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}