{"id":"W2558409621","doi":"10.1107/s2053273314084010","title":"Nidovirus papain-like proteases antagonize the host innate immune response","year":2014,"lang":"en","type":"article","venue":"Acta Crystallographica Section A Foundations and Advances","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"","keywords":"Innate immune system; Biology; Proteases; Arterivirus; Immune system; Ubiquitin; Coronaviridae; Cell biology; Enzyme; Gene; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001883657,0.0003684459,0.0002411086,0.0001071044,0.0001400672,0.0003204485,0.0002098037,0.0002734126,0.001154746],"category_scores_gemma":[0.000150608,0.0001205815,0.0002661993,0.00005821805,0.000205644,0.0002077468,0.0002981901,0.0005470408,0.0003423884],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003087337,"about_ca_system_score_gemma":0.0002239837,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004286839,"about_ca_topic_score_gemma":0.0006678667,"domain_scores_codex":[0.9998208,0.000035234,0.00001177238,0.00003099631,0.00005654258,0.0000447855],"domain_scores_gemma":[0.9999037,0.00001644855,0.00001840591,0.00001452104,0.00001348209,0.00003350899],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000149174,0.00003056305,0.0007783733,0.00009397705,0.00001563271,0.0001805274,0.0000147859,0.0001163864,0.993626,0.0005456242,0.0001560334,0.004293057],"study_design_scores_gemma":[0.0000459948,0.0004024074,0.01525734,0.00001550523,0.00002686829,0.002354765,0.00006799549,0.002373305,0.9606073,0.0005106411,0.01832627,0.00001160975],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9601687,0.01765875,0.01087013,0.0003617837,0.0001416652,0.00007957344,0.0004104323,0.0003603323,0.009948649],"genre_scores_gemma":[0.9923227,0.001365906,0.003211471,0.0001067563,0.00001618764,0.00001988643,0.000185216,0.00001164353,0.002760154],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001154746,"threshold_uncertainty_score":0.003863037,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009971510250604582,"score_gpt":0.2776225471334287,"score_spread":0.2676510368828241,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}