{"id":"W2558470118","doi":"10.1038/ncomms13515","title":"Structural decoding of netrin-4 reveals a regulatory function towards mature basement membranes","year":2016,"lang":"en","type":"article","venue":"Nature Communications","topic":"Axon Guidance and Neuronal Signaling","field":"Neuroscience","cited_by":112,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; University of Lethbridge","funders":"Multiple Sclerosis Society; Deutsche Krebshilfe; Ligue Contre le Cancer; National Institutes of Health; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; Agence Nationale de la Recherche; Deutsche Forschungsgemeinschaft; National Institute of Diabetes and Digestive and Kidney Diseases; Multiple Sclerosis Society of Canada; Melanoma Research Alliance; Institut National Du Cancer; Canadian Institutes of Health Research; National Science Foundation","keywords":"Netrin; Laminin; Axon guidance; Angiogenesis; Cell biology; Basement membrane; Receptor; Biology; Extracellular matrix; Neuroscience; Axon; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008359467,0.0002643558,0.0001380927,0.0001885749,0.0001604681,0.0003149874,0.0002697426,0.0002280529,0.00103592],"category_scores_gemma":[0.0002365764,0.0001351763,0.0002174074,0.00009291014,0.000178892,0.0002649389,0.000202298,0.0004308147,0.0003128567],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005331023,"about_ca_system_score_gemma":0.0003247295,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001632818,"about_ca_topic_score_gemma":0.001451496,"domain_scores_codex":[0.9999546,0.000006589002,0.000002858551,0.00001165747,0.00001194201,0.00001236964],"domain_scores_gemma":[0.9998944,0.00001854748,0.00003749095,0.00001108611,0.00001531152,0.00002316519],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001735289,0.000009914698,0.0005126061,0.00002383558,0.00000580016,0.0002433333,0.00001943749,0.00121815,0.9947627,0.0005221193,0.00005917438,0.002449335],"study_design_scores_gemma":[0.00001330296,0.0001295472,0.009320105,0.000007069815,0.00002758729,0.0003999462,0.00005373789,0.01103506,0.9749627,0.0003629659,0.003674047,0.00001409881],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.992822,0.0004205394,0.004723098,0.00009838656,0.00002259611,0.000008800205,0.0001847017,0.00007885862,0.001641124],"genre_scores_gemma":[0.9877397,0.0005249624,0.007784214,0.0000553344,0.000009350101,0.000008836414,0.0006355811,0.00003736522,0.00320459],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001632818,"threshold_uncertainty_score":0.003867984,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0547831310268918,"score_gpt":0.3143008348198475,"score_spread":0.2595177037929557,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}