{"id":"W2558470118","doi":"10.1038/ncomms13515","title":"Structural decoding of netrin-4 reveals a regulatory function towards mature basement membranes","year":2016,"lang":"en","type":"article","venue":"Nature Communications","topic":"Axon Guidance and Neuronal Signaling","field":"Neuroscience","cited_by":112,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; University of Lethbridge","funders":"Multiple Sclerosis Society; Deutsche Krebshilfe; Ligue Contre le Cancer; National Institutes of Health; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; Agence Nationale de la Recherche; Deutsche Forschungsgemeinschaft; National Institute of Diabetes and Digestive and Kidney Diseases; Multiple Sclerosis Society of Canada; Melanoma Research Alliance; Institut National Du Cancer; Canadian Institutes of Health Research; National Science Foundation","keywords":"Netrin; Laminin; Axon guidance; Angiogenesis; Cell biology; Basement membrane; Receptor; Biology; Extracellular matrix; Neuroscience; Axon; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002297656,0.0001318311,0.000164685,0.000114491,0.0002761531,0.00001753776,0.0008892193,0.0001781895,0.00008415501],"category_scores_gemma":[0.000777663,0.00009118137,0.0000937533,0.0003613006,0.0001589828,0.0002337366,0.0002646038,0.0004186117,0.00001252985],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005510654,"about_ca_system_score_gemma":0.00004967322,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005717335,"about_ca_topic_score_gemma":0.00001796604,"domain_scores_codex":[0.9987109,0.0002186815,0.0003082487,0.0002535349,0.0003216435,0.000186983],"domain_scores_gemma":[0.9977677,0.0005719053,0.000218685,0.001259962,0.0001204395,0.00006131465],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004972086,0.00002533555,0.00161274,0.00002186812,0.00000796911,9.161166e-7,0.0000603863,0.000006793261,0.9608657,0.02696989,0.001096549,0.009282099],"study_design_scores_gemma":[0.0007310355,0.00009224191,0.04874375,0.0002594077,0.0000530602,0.00002221701,0.00008480212,0.0002749125,0.9200216,0.003915663,0.02548098,0.0003203143],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9871102,0.004028147,0.0002214147,0.004919246,0.0005323105,0.0003142993,0.00005614313,0.0001222383,0.00269601],"genre_scores_gemma":[0.9971978,0.0006495759,0.0006809485,0.001116492,0.0000791807,0.00001879707,0.000004902164,0.00001623724,0.0002360306],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04713101,"threshold_uncertainty_score":0.3718268,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0547831310268918,"score_gpt":0.3143008348198475,"score_spread":0.2595177037929557,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}