{"id":"W2558647619","doi":"10.1093/nar/gkw1143","title":"Enhanced non-viral gene delivery by coordinated endosomal release and inhibition of β-tubulin deactylase","year":2016,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":49,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"","keywords":"Transfection; Biology; Gene delivery; Cell biology; Nucleofection; Stem cell; Molecular biology; Cell culture; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003405343,0.0001385285,0.0001581857,0.000104807,0.00009467257,0.00002093939,0.0001757216,0.0002012319,0.00006614962],"category_scores_gemma":[0.0001758177,0.0001081588,0.00006016755,0.0001182529,0.0003254686,0.00001635559,0.0002389046,0.0001427114,0.00004950169],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002639867,"about_ca_system_score_gemma":0.0000968659,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000830058,"about_ca_topic_score_gemma":0.0000149557,"domain_scores_codex":[0.9985566,0.0001402106,0.0002358894,0.0004160197,0.0002649776,0.0003863358],"domain_scores_gemma":[0.999074,0.0000424149,0.00005757445,0.0003198193,0.0003610041,0.0001451582],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005415755,0.00008129941,0.0007261112,0.00001691381,0.000031138,0.000009364615,0.00003158854,4.942172e-7,0.9757011,0.00001009079,0.006735129,0.01611522],"study_design_scores_gemma":[0.001175782,0.001004846,0.00136948,0.00005148408,0.000006041728,0.000006951825,0.00005497114,0.00003097684,0.9949362,0.00005848753,0.001166065,0.0001386814],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974796,0.0004081563,0.0009037675,0.0001923795,0.00003655819,0.0001861016,0.00008825055,0.000008676161,0.0006964848],"genre_scores_gemma":[0.9970574,0.001096628,0.0001379501,0.00005939382,0.00009640989,0.00002501904,0.00007669575,0.00002304207,0.001427504],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01923516,"threshold_uncertainty_score":0.441059,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01504613960155161,"score_gpt":0.2829247718279132,"score_spread":0.2678786322263616,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}