{"id":"W2558730779","doi":"10.3389/fimmu.2016.00564","title":"Type I Interferon Impairs Specific Antibody Responses Early during Establishment of LCMV Infection","year":2016,"lang":"en","type":"article","venue":"Frontiers in Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Institut National de la Recherche Scientifique","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Lymphocytic choriomeningitis; Immunology; Antibody; Hypergammaglobulinemia; Population; Biology; Immune system; Interferon; T cell; Virology; Medicine; CD8","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001739313,0.0003864261,0.000303204,0.0002205872,0.0001206355,0.0002771782,0.0002118672,0.000351475,0.0007664417],"category_scores_gemma":[0.0001387885,0.0001545333,0.0001910989,0.0001109403,0.0002395708,0.0001889273,0.0002184605,0.0008264852,0.0003019486],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003748453,"about_ca_system_score_gemma":0.0002177225,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005679977,"about_ca_topic_score_gemma":0.0007475359,"domain_scores_codex":[0.9997531,0.00004553287,0.00002857006,0.00003833945,0.00004463877,0.00008977397],"domain_scores_gemma":[0.9998177,0.00003636579,0.00005398896,0.00002525212,0.00001367847,0.00005306993],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008572266,0.00001948329,0.0001419326,0.00001168633,0.00000172223,0.00003028527,0.00001043029,0.00001719887,0.9992945,0.00004979326,0.00001187891,0.000325296],"study_design_scores_gemma":[0.00001287243,0.0002840219,0.006347238,0.000009379612,0.00001248693,0.0001722939,0.00003538647,0.0004437825,0.991619,0.00005839871,0.001001896,0.000003226555],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959526,0.001161875,0.001335868,0.000056596,0.00003460799,0.00002207358,0.0002548683,0.00009250924,0.001089109],"genre_scores_gemma":[0.9961013,0.0006646664,0.0009329253,0.00004502316,0.00001291732,0.00003301349,0.0002598325,0.00002585823,0.001924487],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007664417,"threshold_uncertainty_score":0.002719641,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008994544834401664,"score_gpt":0.2346293874405457,"score_spread":0.225634842606144,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}