{"id":"W2558898059","doi":"10.1182/blood.v108.11.762.762","title":"Reduction in Factor VIII Inhibitors Mediated through Tolerogenic Antigen Presentation by immature Dendritic Cells.","year":2006,"lang":"en","type":"article","venue":"Blood","topic":"Hemophilia Treatment and Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"","keywords":"Immunology; Medicine; Antigen; Bone marrow; Immune system; Dendritic cell; Immune tolerance; Immunotherapy; Antigen-presenting cell; Myeloid; Antibody; T cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001467848,0.0003027384,0.0001825468,0.0001498028,0.00009738629,0.0002440785,0.0001445172,0.000206608,0.0009011964],"category_scores_gemma":[0.0001334752,0.0000694003,0.0002161459,0.00008118435,0.0001405774,0.0001081415,0.0001147937,0.0006570707,0.0002599811],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001393319,"about_ca_system_score_gemma":0.0001760656,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002952109,"about_ca_topic_score_gemma":0.0002199838,"domain_scores_codex":[0.999871,0.00002404372,0.000008060753,0.00001893873,0.00003090456,0.0000470378],"domain_scores_gemma":[0.9999173,0.00001145913,0.00002047102,0.00001015246,0.0000134315,0.00002708732],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004677596,0.0001362246,0.0002291593,0.00003567541,0.00000316502,0.00003222141,0.00001294467,0.00004939087,0.9951024,0.00007431395,0.00007406377,0.003782705],"study_design_scores_gemma":[0.0001868473,0.003851262,0.005005777,0.00001075153,0.00003383068,0.000258497,0.00002784456,0.0008795924,0.9858432,0.00007134551,0.003827608,0.00000336714],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957368,0.001070447,0.001246703,0.00007936888,0.00004851537,0.00007380087,0.0002020624,0.0000563164,0.001485877],"genre_scores_gemma":[0.9955789,0.0006815544,0.0009178977,0.00005607458,0.00003260119,0.0000585361,0.0003349782,0.00001074033,0.002328515],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009011964,"threshold_uncertainty_score":0.003014803,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0132648855641505,"score_gpt":0.2762519890032589,"score_spread":0.2629871034391084,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}