{"id":"W2558920446","doi":"10.1182/blood.v116.21.123.123","title":"Induction of Micro RNA-143 and 145 In Pre-Treatment CD34+ Cells From Patients with Myelodysplastic Syndrome (MDS) After In Vitro exposure to Lenalidomide Correlates with Clinical Response In Patients Harboring the Del5q Abnormality","year":2010,"lang":"en","type":"article","venue":"Blood","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Lenalidomide; CD34; Oncology; Medicine; Internal medicine; Cohort; microRNA; Myelodysplastic syndromes; Immunology; Cancer research; Bone marrow; Stem cell; Biology; Multiple myeloma; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001049006,0.0001307894,0.0002021441,0.0002154947,0.0001537724,0.000287447,0.00008448759,0.0002094431,0.002979862],"category_scores_gemma":[0.0002518079,0.0001585004,0.0001287271,0.0001412459,0.0001302315,0.00006803756,0.0001463403,0.0003269447,0.0005285126],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001206928,"about_ca_system_score_gemma":0.00009277319,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002808419,"about_ca_topic_score_gemma":0.0004903294,"domain_scores_codex":[0.999882,0.00002431569,0.00001169339,0.00002866119,0.00003531222,0.00001801526],"domain_scores_gemma":[0.9998986,0.00002501997,0.00002299935,0.00001036387,0.00001445215,0.00002861035],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002122801,0.0001815636,0.04309311,0.00008882651,0.00003577461,0.0004784924,0.0002059671,0.0001055914,0.9470642,0.00005121862,0.0002457613,0.00632662],"study_design_scores_gemma":[0.0001834479,0.004900257,0.6704761,0.00002577572,0.0001173369,0.004339982,0.0003271348,0.0009602132,0.3141916,0.00008225411,0.004381417,0.00001437268],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983919,0.0006795833,0.0002225272,0.00002167339,0.000008738455,0.00001971978,0.0001965882,0.000009395777,0.0004498765],"genre_scores_gemma":[0.9979509,0.0002119284,0.0003021564,0.00003703304,0.00000827613,0.00002859204,0.0007730323,0.000003316486,0.0006847589],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002979862,"threshold_uncertainty_score":0.009968698,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007451592987781739,"score_gpt":0.248005595682963,"score_spread":0.2405540026951813,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}