{"id":"W2559073273","doi":"10.1182/blood.v114.22.1486.1486","title":"Heterogenous Nuclear Ribonucleoprotein L (hnRNPL) Is Required for the Functional Integrity of Hematopoietic Stem Cells.","year":2009,"lang":"en","type":"article","venue":"Blood","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Clinical Research Institute","funders":"","keywords":"Cre recombinase; Biology; Haematopoiesis; Transgene; Molecular biology; Heterogeneous nuclear ribonucleoprotein; RNA splicing; Regulator; Alternative splicing; Stem cell; Cell biology; Conditional gene knockout; Genetically modified mouse; Exon; Gene; Genetics; Phenotype; RNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008585505,0.0002122912,0.0001210022,0.0001508646,0.0001686413,0.0002062616,0.0002007201,0.0002690296,0.004180554],"category_scores_gemma":[0.00008233063,0.0001289419,0.0001394532,0.00006524943,0.0001890541,0.0001285707,0.0002479255,0.0003174401,0.001534568],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001994545,"about_ca_system_score_gemma":0.0001566122,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003824401,"about_ca_topic_score_gemma":0.0007091945,"domain_scores_codex":[0.9999098,0.00001020222,0.00000614579,0.00002907866,0.00002605528,0.0000186553],"domain_scores_gemma":[0.9998351,0.00001999815,0.00005833554,0.00001505676,0.00001117005,0.00006029813],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003572509,0.000004801172,0.0002246017,0.00001198058,0.00000129428,0.00004586116,0.000004434264,0.00001330884,0.998405,0.00007874619,0.0000731691,0.001101115],"study_design_scores_gemma":[0.00001526687,0.0001906469,0.03205727,0.00001128717,0.00001634331,0.0006253081,0.00004009735,0.0008271314,0.9564138,0.00011712,0.009680775,0.000004901774],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9809378,0.002328619,0.006170471,0.0002799307,0.00007575972,0.00005392068,0.001858301,0.0003133108,0.007981922],"genre_scores_gemma":[0.9687632,0.001048904,0.003567549,0.0001241712,0.00002605258,0.00004762745,0.003652841,0.0001013021,0.02266831],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004180554,"threshold_uncertainty_score":0.01398534,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02246361417289121,"score_gpt":0.2498614179005517,"score_spread":0.2273978037276605,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}