{"id":"W2559088801","doi":"10.2337/db16-0680","title":"Improved Glucose Homeostasis in Obese Mice Treated With Resveratrol Is Associated With Alterations in the Gut Microbiome","year":2016,"lang":"en","type":"article","venue":"Diabetes","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":210,"is_retracted":false,"has_abstract":true,"ca_institutions":"The Metabolomics Innovation Centre; McMaster University; Population Health Research Institute; University of Alberta","funders":"Institute of Circulatory and Respiratory Health; Natural Sciences and Engineering Research Council of Canada; Genome Canada; Canadian Diabetes Association","keywords":"Akkermansia; Resveratrol; Lachnospiraceae; Microbiome; Glucose homeostasis; Akkermansia muciniphila; Gut flora; Biology; Homeostasis; Bacteroidaceae; Endocrinology; Bacteroides; Gut microbiome; Internal medicine; Immunology; Medicine; Pharmacology; Diabetes mellitus; Bioinformatics; Biochemistry; Insulin resistance; Bacteria","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001998088,0.0001672664,0.0001716079,0.00008604764,0.00006865348,0.00003654322,0.0001682959,0.0001202629,0.00001496567],"category_scores_gemma":[0.00003897609,0.00008729358,0.00003302867,0.0002814127,0.00007950286,0.000008834699,0.00002486236,0.00008482174,0.000006219725],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004433141,"about_ca_system_score_gemma":0.00009412708,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001157947,"about_ca_topic_score_gemma":0.00143709,"domain_scores_codex":[0.9989318,0.0001280847,0.000182926,0.0003139946,0.00005934943,0.0003838498],"domain_scores_gemma":[0.9994839,0.00004518308,0.00007559809,0.0002824023,0.00007008409,0.00004280519],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000783599,0.00013785,0.04459614,0.000008508284,0.00004223783,0.000003637184,0.0001947668,8.067896e-7,0.9537322,0.000003149789,0.0007150965,0.0004872644],"study_design_scores_gemma":[0.003374774,0.0008425873,0.1031117,0.0001633718,0.00002830759,0.000003742119,0.0001301903,0.00001783776,0.8902971,0.000008626699,0.001735672,0.0002861383],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997443,0.000716392,0.000007976444,0.0012308,0.00001269146,0.0003374369,0.0001771966,0.000009086043,0.00006548409],"genre_scores_gemma":[0.9981281,0.0001297299,0.000077088,0.001119,0.00002826634,0.00006048383,0.0001992065,0.00002024314,0.0002378713],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06343513,"threshold_uncertainty_score":0.3559729,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006280210348698974,"score_gpt":0.2208635836132632,"score_spread":0.2145833732645642,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}