{"id":"W2559260065","doi":"10.1182/blood.v104.11.4966.4966","title":"An Exaggerated B Cell CpG Response in Human Chronic Graft-versus-Host Disease: A Potential Mechanism and Biomarker for Diagnosis of Chronic GVHD.","year":2004,"lang":"en","type":"article","venue":"Blood","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Immunology; Graft-versus-host disease; Medicine; Immune system; Transplantation; TLR9; Flow cytometry; Peripheral blood mononuclear cell; Biology; Internal medicine; DNA methylation; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009236667,0.0004265184,0.0003392677,0.001406261,0.0001865208,0.0004320053,0.000319175,0.0006096886,0.003623475],"category_scores_gemma":[0.0003947096,0.0001944081,0.0001319395,0.0006229416,0.0003513627,0.0003358203,0.0003147754,0.0006417971,0.0008933751],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001563855,"about_ca_system_score_gemma":0.00008105215,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001190425,"about_ca_topic_score_gemma":0.00009355605,"domain_scores_codex":[0.9996443,0.0001485462,0.00002646672,0.00006786066,0.00006577726,0.00004703799],"domain_scores_gemma":[0.9997124,0.00005489204,0.0000955191,0.00003177332,0.00003672261,0.00006861203],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.003114412,0.0004827708,0.1579553,0.000480038,0.00005984716,0.001227588,0.0001128856,0.00009555435,0.8125526,0.0002865234,0.0006610154,0.02297151],"study_design_scores_gemma":[0.0002558932,0.004937862,0.7826931,0.0001809034,0.0001645026,0.0207414,0.0003626332,0.001975555,0.1783557,0.0009375992,0.009371531,0.00002319559],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9845728,0.009144791,0.002799678,0.0001274817,0.00006142102,0.00009937854,0.0003250591,0.0001299797,0.002739424],"genre_scores_gemma":[0.9970595,0.0007224858,0.001095839,0.0001039309,0.00004953485,0.00005116748,0.0002589894,0.00001020846,0.0006482435],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003623475,"threshold_uncertainty_score":0.0121218,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01536356186965415,"score_gpt":0.2796392379094252,"score_spread":0.264275676039771,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}