{"id":"W2559525672","doi":"10.1182/blood.v114.22.2221.2221","title":"Single Nucleotide Polymorphism (SNP) Approach of Multiple Candidate Pathways Predicting the Risk of Acute / Chronic Graft-Versus-Host Disease or Transplant Outcomes Following Allogeneic Hematopoietic Stem Cell Transplantation: Potential Involvement of Nuclear Factor Kappa-B (NFKB), Platelet-Derived Growth Factor (PDGF) and Transforming Growth Factor-Beta (TGF-β) Pathway with Chronic Graft-Versus-Host Disease Graft-Versus-Host Disease.","year":2009,"lang":"en","type":"article","venue":"Blood","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Hematopoietic stem cell transplantation; Immunology; Graft-versus-host disease; Transplantation; Single-nucleotide polymorphism; Medicine; Biology; Internal medicine; Genotype; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002815996,0.0002931195,0.0002019695,0.000787134,0.0002526144,0.0002723075,0.0001508282,0.0002082253,0.001839584],"category_scores_gemma":[0.0004227131,0.0000897845,0.0003390378,0.0006483476,0.0001684947,0.00006395057,0.0001418574,0.0002914667,0.0002397253],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002020499,"about_ca_system_score_gemma":0.0004146607,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003557793,"about_ca_topic_score_gemma":0.007636585,"domain_scores_codex":[0.9998569,0.00003030847,0.00001427883,0.00004013467,0.00003525006,0.00002303826],"domain_scores_gemma":[0.999675,0.0001087206,0.0001038921,0.00001162198,0.00003204985,0.00006863585],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0007658478,0.00008574115,0.9637473,0.00004171265,0.0001809442,0.000359307,0.0001050569,0.0003095686,0.02773864,0.00004316116,0.0001551343,0.006467754],"study_design_scores_gemma":[0.00001856282,0.0002998968,0.9933807,0.000009422279,0.0001430067,0.0006157126,0.00009757976,0.001182338,0.003870517,0.00005996272,0.000316714,0.000005669454],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9988739,0.0001997283,0.0003442499,0.00003046552,0.00000560051,0.000009148683,0.0003560832,0.000004211174,0.0001767481],"genre_scores_gemma":[0.998204,0.00008211211,0.0009339425,0.00002090605,0.000006649886,0.000009729453,0.0004225834,0.000001985125,0.0003180312],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003557793,"threshold_uncertainty_score":0.007074177,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01866848789295794,"score_gpt":0.2191365289335273,"score_spread":0.2004680410405694,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}