{"id":"W2559587137","doi":"10.1093/neuonc/now212.003","title":"ACTR-04. RESULTS OF THE INTERIM ANALYSIS OF THE EORTC RANDOMIZED PHASE III CATNON TRIAL ON CONCURRENT AND ADJUVANT TEMOZOLOMIDE IN ANAPLASTIC GLIOMA WITHOUT 1p/19q CO-DELETION, AN INTERGROUP TRIAL","year":2016,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network; Princess Margaret Cancer Centre","funders":"","keywords":"Temozolomide; Interim analysis; Medicine; Internal medicine; Oncology; Glioma; Adjuvant; Clinical endpoint; Randomized controlled trial; Chemotherapy; Cancer research","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005630826,0.001076083,0.001797407,0.0004230552,0.0003222057,0.001114119,0.0007066395,0.001346696,0.01365513],"category_scores_gemma":[0.005520373,0.0003907435,0.001681558,0.00043692,0.0004250661,0.0005924572,0.0003320749,0.002796949,0.002726984],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006808595,"about_ca_system_score_gemma":0.001429497,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007721618,"about_ca_topic_score_gemma":0.002653247,"domain_scores_codex":[0.9971866,0.002204397,0.00008224886,0.0001518172,0.0002103401,0.000164647],"domain_scores_gemma":[0.9972063,0.001035294,0.0005059319,0.0003263171,0.0002495607,0.0006766337],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8921163,0.004466426,0.003062166,0.0008856984,0.002017707,0.0001482805,0.0000423307,0.002013243,0.002863924,0.000984451,0.04654697,0.04485241],"study_design_scores_gemma":[0.8272107,0.1045387,0.02153258,0.0001930176,0.004537656,0.0003015362,0.00003851651,0.003371192,0.002323349,0.001972903,0.03392757,0.00005223524],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7448214,0.02278298,0.007368976,0.01074361,0.006228036,0.01752378,0.1037604,0.001512872,0.08525795],"genre_scores_gemma":[0.8419907,0.004339586,0.01005898,0.009036786,0.001468611,0.01646691,0.07731757,0.0005315539,0.03878926],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01365513,"threshold_uncertainty_score":0.04568094,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03145773734539179,"score_gpt":0.3595383140764256,"score_spread":0.3280805767310338,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}