{"id":"W2559607846","doi":"10.1182/blood.v108.11.2810.2810","title":"The Vascular Endothelial Growth Factor (VEGF) Autocrine Survival Signaling Pathway in Chronic Lymphocytic Leukemia (CLL) Is Regulated by Lysophosphatidic Acid (LPA).","year":2006,"lang":"en","type":"article","venue":"Blood","topic":"Chronic Lymphocytic Leukemia Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"","keywords":"Autocrine signalling; Vascular endothelial growth factor; Cancer research; Angiogenesis; Lysophosphatidic acid; Vascular endothelial growth factor A; Biology; Chronic lymphocytic leukemia; Protein kinase B; Receptor; Internal medicine; Endocrinology; Signal transduction; Immunology; Leukemia; Cell biology; Medicine; VEGF receptors","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001253283,0.0002571582,0.0001554695,0.0002394717,0.0001704281,0.0002609586,0.00007685761,0.000218672,0.0008165474],"category_scores_gemma":[0.00007812169,0.0001082795,0.0001644415,0.0001848216,0.0002002409,0.0001947715,0.0001939986,0.0004777097,0.0002818311],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003400304,"about_ca_system_score_gemma":0.0001897299,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005108909,"about_ca_topic_score_gemma":0.0006973579,"domain_scores_codex":[0.9999329,0.00001617512,0.000006629374,0.00001126904,0.00001326004,0.00001976152],"domain_scores_gemma":[0.9999514,0.000005765906,0.00001864757,0.000002762173,0.000007492342,0.00001395635],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006060094,0.00004814808,0.00136844,0.0001144202,0.000008384743,0.0001786211,0.00002570269,0.00005838745,0.9929578,0.00009379283,0.0001612321,0.004378973],"study_design_scores_gemma":[0.0001964225,0.00131303,0.06440826,0.0000332737,0.00009899884,0.003380552,0.0001652766,0.001274667,0.9142495,0.000429302,0.01443166,0.00001917256],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9844275,0.01296749,0.001160797,0.0002317327,0.00004840863,0.00001564161,0.0003173912,0.00007138403,0.0007596179],"genre_scores_gemma":[0.9945362,0.003462878,0.0007021667,0.0000630917,0.00001695056,0.00002696789,0.0003537563,0.000006064192,0.0008319976],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008165474,"threshold_uncertainty_score":0.002731621,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0108530413350174,"score_gpt":0.2417009393627176,"score_spread":0.2308478980277002,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}