{"id":"W2559683905","doi":"10.1182/blood.v106.11.4816.4816","title":"Generation of a Fully Human High Affinity Neutralizing Antibody Against MT-SP1/Matriptase and Its Potential Role for the Treatment of B Cell Lymphoma.","year":2005,"lang":"en","type":"article","venue":"Blood","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Helix Biopharma (Canada)","funders":"","keywords":"Molecular biology; Biology; Antibody; Plasminogen activator; Cell culture; Serine protease; Cancer research; Protease; Biochemistry; Enzyme; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004744337,0.0006762987,0.0003383547,0.0003116615,0.0001263297,0.0002144448,0.0005521483,0.0006691696,0.001504378],"category_scores_gemma":[0.0002493464,0.0001899768,0.0005025117,0.0001667865,0.0001245048,0.0001744853,0.0002189292,0.0008905254,0.0005671832],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003176469,"about_ca_system_score_gemma":0.0002169425,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008062565,"about_ca_topic_score_gemma":0.000575707,"domain_scores_codex":[0.9998112,0.00004033365,0.00001246905,0.00003305804,0.00005006858,0.00005277127],"domain_scores_gemma":[0.9998858,0.00002415453,0.00001776633,0.00001341234,0.00002875768,0.000030114],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001379996,0.0001394787,0.0001043332,0.00005174151,0.0000145982,0.00006288621,0.00001274196,0.0001109066,0.9956751,0.00006346254,0.0001253567,0.003501404],"study_design_scores_gemma":[0.0003746498,0.003015644,0.00231465,0.00001672341,0.0001193538,0.001184514,0.00001757305,0.002792039,0.9794866,0.00006683091,0.0106022,0.00000920543],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9610704,0.007496249,0.02606685,0.0004401928,0.0002244007,0.000496799,0.0008297472,0.0002831979,0.003092138],"genre_scores_gemma":[0.9757497,0.00241818,0.01506429,0.0002611655,0.00009093199,0.0002346418,0.002706606,0.00004569628,0.003428668],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001504378,"threshold_uncertainty_score":0.005032718,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03661091635409301,"score_gpt":0.3130703993131619,"score_spread":0.2764594829590689,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}