{"id":"W2559744957","doi":"10.1107/s2053273314084964","title":"The trans-membrane 17βHSD7: Kinetic study and preliminary crystallization data","year":2014,"lang":"en","type":"article","venue":"Acta Crystallographica Section A Foundations and Advances","topic":"Hormonal Regulation and Hypertension","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre hospitalier universitaire de Québec","funders":"","keywords":"Chemistry; Crystallization; Enzyme kinetics; Enzyme; Kinetics; Cofactor; Dehydrogenase; Steady state (chemistry); Transmembrane protein; Cholesterol oxidase; Chromatography; Biochemistry; Active site; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005003206,0.0005468154,0.0007478693,0.0002552377,0.0004014847,0.0004339038,0.0006892574,0.0004880978,0.001644883],"category_scores_gemma":[0.0005809538,0.0001906775,0.0003688051,0.001094009,0.0001834558,0.000303523,0.0002089704,0.0006218123,0.001722935],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009378265,"about_ca_system_score_gemma":0.0005352974,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007637402,"about_ca_topic_score_gemma":0.004963716,"domain_scores_codex":[0.9997659,0.00004066362,0.00002936196,0.00004603299,0.00007905894,0.00003904594],"domain_scores_gemma":[0.9997001,0.0000507773,0.00002219261,0.00002556464,0.000161478,0.00003996072],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001010171,0.0003737534,0.004974015,0.0009878788,0.0001140819,0.0007705012,0.0005287058,0.002148708,0.9609371,0.0009912214,0.004861015,0.02230295],"study_design_scores_gemma":[0.00009146795,0.000394744,0.01156222,0.0000534182,0.0001095154,0.0009520623,0.0003133508,0.008981642,0.9184576,0.0002932364,0.05872446,0.00006642724],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9458473,0.01979479,0.01166959,0.001046826,0.0001739862,0.0002145506,0.01487491,0.000398433,0.005979626],"genre_scores_gemma":[0.8415629,0.03028537,0.03673291,0.0002647187,0.00009974142,0.0002646902,0.07688446,0.0003428522,0.01356236],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007637402,"threshold_uncertainty_score":0.01518589,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02252688764209962,"score_gpt":0.2853506497208959,"score_spread":0.2628237620787963,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}